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Original Article

Clinical Study of Effectiveness Topiramate in Children with Intractable Epilepsy

Young Mi Choi, Sa Jun Chung

Clin Exp Pediatr. 2001;44(1):62-67. Published online January 15, 2001

Purpose : Topiramate(TPM) is a new anticonvulsant with multiple action mechanisms which should theoretically represent a wide therapeutic spectrum. However, there is still little clinical experience of its use in Asian children with epilepsy. Methods : The patients were total 96 children who were treated with more than 2 anticonvulsants but poorly controlled seizure activity. TPM was given as add-on therapy...

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