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Review Article

Efficacy and effectiveness of pneumococcal conjugate vaccine in children

Hoan Jong Lee

Clin Exp Pediatr. 2006;49(3):235-241. Published online March 15, 2006

Streptococus pneumoniae is an important cause of invasive infections as well as non-invasive infections such as acute otitis media and sinusitis both in children and adults. Resistance of S. pneumoniae to multiple antimicrobials is increasing and poses therapeutic challenges, and prevention became more important. 23-valent polysaccharide vaccine has been used for the last several decades, but is not effective in...

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