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Original Article
Effect of Low-Dose Aspirin Therapy on Platelet Aggregation in Kawasaki Disease
Ju Yeon Yeo, Heon Eui Le, Young Mi Hong, Ki Sook Hong, Wha Soon Chung
Clin Exp Pediatr. 1999;42(4):510-518.   Published online April 15, 1999
Purpose : Aspirin(acetylsalicylic acid) has been used to treat unstable angina and acute myocardial infarction in adults and Kawasaki disease in children. The antithrombotic effect of aspirin was attributed to its ability to inhibit platelet aggregation by inhibiting platelet cyclooxygenase, which leads to decreased thromboxane synthesis. The purpose of this study was to evaluate the effect on the platelet aggregation...
A case of thrombasthenia.
Yong Bae Suh, Eun Kyoung Sohn, Yong Mook Choi, Chang Il Ahn
Clin Exp Pediatr. 1991;34(2):287-291.   Published online February 28, 1991
Glanzmann’s thrombasthenia is a congenital disorder of platelet function with missing or abnormal platelet plasma membrane glycoprotein Ilb/IIIa which function as receptors for fibrinogen and other high-molecular-weight adhesive proteins which are important for platelet aggregation. We have experienced a case of thrombasthenia in a 12 month old male whose chief complaints were easy bruising and frequent epistaxis. The beeding time was prolonged in the...
Two cases of Glanzmann's thrombasthenia in brother.
Won Mo Yang, Hyung Kook Ham, Mee Kyung Namgoong, Baek Keun Lim, Hong Sup Yoon, Kab Joon Yoon
Clin Exp Pediatr. 1989;32(11):1574-1580.   Published online November 30, 1989
Glanzmann’s thrombasthenia is rare congenital bleeding disorder of autosomal recessive trait. We experienced two cases of Glanzmann’s thrombasthenia in brother. The mother and elder brother had no history of bleeding tendency. But 10 year-old and 7 year-old younger brothers had frequent epistaxis, gum bleeding and easy bruisability. On platelet aggregation test, mother and elder brother appeared normal responses, but the younger brothers appeared no responses...
A Case of Glanzmann's Thromboasthenia.
Hee Kyung Park, Kyung Hee Kim, Sang Man Shin, Sang Jhoo Lee
Clin Exp Pediatr. 1987;30(2):223-228.   Published online February 28, 1987
Glanzmann’s Thromboasthenia is a rare autosomal recessive hemorrhagic disorder characterized by chronic nonthrombocytopenic purpura, a prolonged bleeding time, and deficient or absent clot retraction. The major underlying abnormality is defective first phase aggregation of platelets, which are unresponsive to ADP in any concentration. The authors experienced one case of Glanzmann’s Thromboasthenia in a 8 year 10 month old female, who had frequent epistaxis and gingival...
A Case of Glanzmann's Thrombathenia.
Saeng Gu Cho, Won Ho Kang, Young Youn Choi, Tai Ju Hwang, Dong Wook Ryang, Joo Young Yoo
Clin Exp Pediatr. 1986;29(6):668-673.   Published online June 30, 1986
The authors experienced a 6-year-old female patient with Glanzmann’s Thrombathenia and cerebral palsy. She was admitted with epistaxis, gingival bleeding and easy bruisability. Platelets of patients showed complete absence of aggreration in response to ADP, collagen, and epinephrine but only first aggregation to ristocetin. After platelet aggregation test, bone marrow aspiration, and electron micrographic examination, she was proved as...
Case Report
Three Cases of Glanzmann's Thrombasthenia.
Sung In Baek, Myung Chul Hyun, Haeng Mi Kim, Kun Soo Lee, Doo Hong Ahn, Hyo Jin Chun, Jay Sik Kim
Clin Exp Pediatr. 1985;28(11):1153-1157.   Published online November 30, 1985
We experienced 3 cases of Glanzmann' s thrombasthenia of 2 year-old boy, 4 year-old boy, and 5 year-old girlt who represented with frequent epistaxis and petechia. The later two of them are brother and sister.Laboratory findings were characterized by normal platelet counts, markedly diminished clot retraction, prolonged bleeding time, positive Rumpel-Leede test, abnormal platelet adhesion to glass, and complete failure...
A case of Thrombasthenia.
Sung Sook Cho, Kye Tai Kim, Don Hee Ahn, Keun Chan Sohn
Clin Exp Pediatr. 1981;24(1):88-93.   Published online January 15, 1981
A 6 year 6month-old boy was admitted with complains of severe spontaneou epistaxis and easy brusability. He was one of five siblings, and two of them died of recurred severe epistaxis at their age of six years. There was no history of bleeding tendency to his antecedents and parents, whose marriage was unrelated. Platelet count and partial thromboplastin time were...
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