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Original Article

Effects of Intestinal Ischemia on Intestinal Mucosal Damage and Effects of Interleukin-10 in Young Murine Model

Young-Shil Park, Dong-Chul Kim, Chung-Sik Chun

Clin Exp Pediatr. 2004;47(3):319-324. Published online March 15, 2004

Purpose : Intestinal vascular ischemia is the most probable pathogenesis in the development of necrotizing enterocolitis in prematures. The authors studied the histology of intestinal mucosal damage by clamping the superior mesenteric artery in 35 rats, and, analyzed the histologic scores between young rats(I) and adult rats(II) groups according to clamping times(15, 30 and 60 minutes) and compared the effect...

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