Clinical and Experimental Pediatrics

Original Article

Pulmonology

High-Risk CCL14 lineage drives severe Mycoplasma pneumoniae pneumonia in children: a study in central China

Chunbo Hao, Zijie Li, Yanjuan Yu, Song Wang, Genhao Wang, Gaijing Jia, Tiantian Sun, Shouhang Chen, Yang Wu, Yu Tang, Fang Wang, Guangcai Duan, Yuefei Jin

Clin Exp Pediatr. 2026;69(6):497-507. Published online April 10, 2026

Web of Science 1 Crossref 1

Question: Are the predominant circulating strains of Mycoplasma pneumoniae associated with disease severity and clinical indicators?
Finding: The common cluster label 14 (CCL14) lineage was a high-risk clone circulating in central China that demonstrated a strong association between severe pediatric pneumonia and a distinct hyperinflammatory profile.
Meaning: Targeted molecular surveillance of the CCL14 lineage may facilitate early risk stratification and guide clinical management to reduce the burden of severe disease.

DOI: https://doi.org/10.3345/cep.2025.02796

Infection

Uropathogenic Escherichia coli ST131 in urinary tract infections in children

Ki Wook Yun, Mi-Kyung Lee, Wonyong Kim, In Seok Lim

Clin Exp Pediatr. 2017;60(7):221-226. Published online July 31, 2017

Crossref 12

Purpose

Escherichia coli sequence type (ST) 131, a multidrug-resistant clone causing extraintestinal infections, has rapidly become prevalent worldwide. However, the epidemiological and clinical features of pediatric infections are poorly understood. We aimed to explore the characteristics of ST131 Escherichia coli isolated from Korean children with urinary tract infections.

Methods

We examined 114 uropathogenic E. coli (UPEC) isolates from children hospitalized at Chung-Ang University...

DOI: https://doi.org/10.3345/kjp.2017.60.7.221

Molecular typing of uropathogenic Escherichia coli isolated from Korean children with urinary tract infection

Ki Wook Yun, Do Soo Kim, Wonyong Kim, In Seok Lim

Clin Exp Pediatr. 2015;58(1):20-27. Published online January 31, 2015

Crossref 28

Purpose

We investigated the molecular types of uropathogenic Escherichia coli (UPEC) by using conventional phylogrouping, multilocus sequence typing (MLST), and fimH genotyping.

Methods

Samples of patients younger than 18 years of age were collected from the Chung-Ang University Hospital over 2 years. Conventional phylogenetic grouping for UPEC strains was performed by polymerase chain reaction (PCR). Bacterial strain sequence types (STs) were classified on...

DOI: https://doi.org/10.3345/kjp.2015.58.1.20

Cited By 59	Prevalence of anxiety, depression, and stress among parents of neonates admitted to neonatal intensive care unit: a systematic review and meta-analysis
Cited By 37	Community-acquired pneumonia in children: updated perspectives on its etiology, diagnosis, and treatment
Cited By 37	Metabolic complications of obesity in children and adolescents
Cited By 34	Microplastic and human health with focus on pediatric well-being: a comprehensive review and call for future studies
Cited By 34	Neonatal family-centered care: evidence and practice models

Search