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Review Article

Growth hormone treatment and risk of malignancy

Hyun-Wook Chae, Duk-Hee Kim, Ho-Seong Kim

Clin Exp Pediatr. 2015;58(2):41-46. Published online February 28, 2015

Growth hormone (GH) treatment has been increasingly widely used for children with GH deficiencies as the survival rate of pediatric patients with malignancies has increased. Both GH and insulin-like growth factor-I have mitogenic and antiapoptotic activity, prompting concern that GH treatment may be associated with tumor development. In this review, the authors examined the relationship between GH treatment and cancer...

DOI: https://doi.org/10.3345/kjp.2015.58.2.41

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