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Original Article

Risk Factors for Hyperglycemia in Children with Leukemia Receiving L-asparaginase

Min Joong Kwon, Ho Sung Kim, Kir Young Kim, Duk Hi Kim

Clin Exp Pediatr. 1994;37(6):740-745. Published online June 15, 1994

Hyperglycemia is a well-recognized side effect of L-asparaginase in remission induction therapy of acute lymphocytic leukemia. Since hyperglycemia has preceded fatal diabetic ketoacidosis or hyperosmotic nonketotic coma in some patients, early detection and treatment of this complication are important. We determined retrospectively the risk of hyperglycemia in 117 patients with leukemia who had received L-asparaginase (& prednisolone). The results were as...

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