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Case Report

A Case of Dubin-Johnson Syndrome in Childhood.

Young Hoon Kim, Young Soo Kim, Sang Kyu Park, Jung Ki Seo, Yong Choi

Clin Exp Pediatr. 1986;29(11):1275-1280. Published online November 30, 1986

A case of Dubin-Johnson syndrome in 10-year-old Korean male child was presented. The presenting symptom was dark-colored urine for several years. Laboratory findings showed increased bilirubin, especially direct-reacting bilirubin, and abnormal urinary coproporphyrin pattern (coproporphyrin I : 58%, coproporphyrin JK : 42%). Needle biopsy specimen of liver showed dark-brownish pigmentation in liver cells but was otherwise normal histologically.

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