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Original Article

On the Permeability of INH through Blood-Brain Barrier

Joong Sik Kim, Young Pyo Hong

Clin Exp Pediatr. 1974;17(10):683-687. Published online October 31, 1974

Serum and cerebrospinal fluid INH levels were studied in tuberculous and non tuberculous meningitis cases following oral administration of INH 4 mg. per kg. of body weight. The measurements were done by the biological method. The INH levels 1 hour after administration were about half of serum in prolonged convulsion and tuberculous meningitis cases. Two hours after administration, the cerebrospinal...

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