Clinical and Experimental Pediatrics

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Original Article

Etretinate Induced Cardiovascular Malformations in Mouse Embryo

Il Kyung Kim, Chang Sung Son, Young Chang Dockgo, Yong Hyuk Jeon

Clin Exp Pediatr. 1995;38(10):1370-1377. Published online October 15, 1995

Purpose : Etretinate(Tigason? is an aromatic retinoid currently in therapeutic use for psoriasis but studies have shown that it is a potent teratogen in human and in experimental animal. So we carried this study to observe teratogenic effects of etretinate and to search a possibility of etretinate for using as an experimental model to induce cardiovascular malformation. Methods : In order...

Detection of Mycoplasma pneumoniae in clinical Samples from Pediatric Patients by Polymerase Chain Reaction

Baik-Lin Eun, Sang Hee Park, Young Chang Dockgo, Sang Chul Seong

Clin Exp Pediatr. 1995;38(8):1077-1086. Published online August 15, 1995

Purpose : Mycoplasma pneumoniae is a common cause of a wide rage of upper and lower respiratory tract infections, especially in children and young adults. Routine laboratory diagnosis of M.pneumoniae infection is based mainly on serology and, to lesser extent, on cultivation. The cultivation of M.pneumoniae, a fastidious microorganism, is time-consuming and may require 1-3 weeks for results. Serological procedures...

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