Clinical and Experimental Pediatrics

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Original Article

Effect of Low-Dose Aspirin Therapy on Platelet Aggregation in Kawasaki Disease

Ju Yeon Yeo, Heon Eui Le, Young Mi Hong, Ki Sook Hong, Wha Soon Chung

Clin Exp Pediatr. 1999;42(4):510-518. Published online April 15, 1999

Purpose : Aspirin(acetylsalicylic acid) has been used to treat unstable angina and acute myocardial infarction in adults and Kawasaki disease in children. The antithrombotic effect of aspirin was attributed to its ability to inhibit platelet aggregation by inhibiting platelet cyclooxygenase, which leads to decreased thromboxane synthesis. The purpose of this study was to evaluate the effect on the platelet aggregation...

Case Report

A Case of Chronic Granulomatous Disease

So Young Lee, Dae Chul Kim, Sung Hee Oh, Hahng Lee, Hyang Eun Sohn, Wha Soon Chung, Young Hyeh Ko, Moon Hyang Park

Clin Exp Pediatr. 1992;35(5):704-712. Published online May 15, 1992

Chronic granulomatous disease (CGD) is a hereditary disorder of neutrophil with defective killing and digesting of ingested catalase-positive bacteria or fungi in spite of normal phagocytosis. Dissemination of ingested live organisms results in multiple granuloma in reticuloendothelial system and multiple abscesses manifested by recurrent pus-draining suppurative lymphadenopathy, subcutanous abscess, or impetiginous skin rahses, pheumonitis, and hepatosplenomegaly, ultimately resulting in death. Two...

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