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Infliximab treatment for a patient with refractory Kawasaki disease

Hyo-Jung Yu, Soo-Jin Lee, Sejung Sohn

Clin Exp Pediatr. 2006;49(9):987-990. Published online September 15, 2006

Intravenous immunoglobulin (IVIG) infusion is an effective therapy for acute Kawasaki disease (KD). Nonetheless, approximately 10 percent to 20 percent of patients have persistent or recrudescent fever despite IVIG treatment, leading to a higher risk for coronary artery aneurysms (CAA). This unresponsiveness may pose a challenge to the clinicians. Tumor necrosis factor-α levels are elevated in the acute phase of...

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