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Original Article

Natural History of Chronic Hepatitis B in Children

Yuria Kim, Seoung Yeon Baek, Ji Hyun Eom, Ki Sup Chung

Clin Exp Pediatr. 2004;47(3):282-289. Published online March 15, 2004

Purpose : We investigated the spontaneous seroconversion rate of hepatitis B viral markers and predictive factors affecting seroconversion in children with chronic hepatitis B. Methods : The study population included 214 children diagnosed as chronic hepatitis B, with positive HBsAg, HBeAg and HBVDNA over six months, and all patients had a family history of chronic Hepatitis B. They were followed between...

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