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Original Article

Surfactant Protein SP-A, B, and C: Purification and Biochemical Characterization

Chong-Woo Bae, Yong-Mook Choi, Joo Hyun Kang, Kil Lyong Kim, Kyung Soo Hahn

Clin Exp Pediatr. 1996;39(2):218-229. Published online February 15, 1996

Purpose : Several kinds of exogenous pulmonary surfactants (SF), either synthetic or animalderived, are being used for the replacement therapy in respiratory distress syndrome (RDS) of newborn, especially in premature infants, and improved the neonatal mortality and morbidity. Because synthetic preparations are lack of surfactant protein (SP) and animal-derived preparations cause immunogenecity of heterogenous SP, there have been great necessity for the development of next...

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