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Case Report
A Case of Recurrent Herpes Simplex Virus Disease of a Preterm Infant, Who Needed Continuous Oral Acyclovir Suppressive Therapy
Sung Seok Kim, Ki Woong Hong, Eun Ryoung Kim, Young-Don Kim, Kyoo Man Lee
Clin Exp Pediatr. 2003;46(9):939-949.   Published online September 15, 2003
Neonatal herpes simplex virus(HSV) infections result in significant morbidity and mortality. Although acyclovir treatment has improved survival, severe neurological sequelae can occur in the majority of survivors. HSV infections limited to the skin, eyes and mouth(SEM) can cause neurologic impairment. A direct correlation exists between the development of neurologic deficits and the frequency of cutaneous HSV recurrences. National Institutes of...


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