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Case Report

Two Cases of Doxorubicin-induced Dilated Cardiomyopathy

Jin Won Park, Kyeong Ah Lee, Yong Woon Paik, Hyun Kee Chung, Jae Sun Park

Clin Exp Pediatr. 1992;35(6):822-828. Published online June 15, 1992

Doxorubicin is an anthracycline antibiotic with a broad spectrum of activity in human neoplasms. However, this agent may cause, frequently, irreversible congestive left ventricular failure. We have experienced 2 cases of doxorubicin induced cardiomyopathy in one patient with multiple eosinophilic granuloma and another patient with T cell leukemia. Total dosage of doxorubicin was 295 mg/M2 for the 6 months duration and...

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