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Case Report

Two Pediatric Patients with Neutropenia and Thrombocytopenia Associated with Parvovirus B19 Infection

Dong Koo Kim, Young Dai Kim, Ho Jun Lim, Sung Hee Oh, Hahng Lee

Clin Exp Pediatr. 2004;47(3):338-342. Published online March 15, 2004

Parvovirus B19, a member of the Erythrovirus genus, is the only member of the Parvoviridae family known to be pathogenic in humans. Haematological consequences of B19 infection arise due to a direct cytotoxic effect on erythroid progenitors in bone marrow, resulting in interruption of erythrocyte production. The physiology of host haematopoiesis and competence of the immune response each determines clinical...

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