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Fatal plastic bronchitis with eosinophilic casts in a previously healthy child

Young Kuk Cho, Soo Min Oh, Woo-Yeon Choi, Eun Song Song, Dong-Kyun Han, Young-Ok Kim, Jae Sook Ma

Clin Exp Pediatr. 2009;52(9):1048-1052. Published online September 15, 2009

Plastic bronchitis is a rare disease characterized by the recurrent formation of branching mucoid bronchial casts that are large and more cohesive than those that occur in ordinary mucus plugging. Casts may vary in size and can be spontaneously expectorated, but some require bronchoscopy for removal. Plastic bronchitis can therefore present as an acute life-threatening emergency if obstruction of the...

Long-term recombinant interferon-γ treatment in 2 cases of osteopetrosis

Dong-Yun Kim, Dong-Kyun Han, Hee-Jo Baek, Sung-Taek Jung, Hoon Kook, Tai-Ju Hwang

Clin Exp Pediatr. 2007;50(11):1129-1133. Published online November 15, 2007

Osteopetrosis, a rare osteosclerotic bone disease characterized by a defect in osteoclast function and the reduced generation of superoxide by leukocytes, can be classified into several types based on their mode of inheritance, age of onset, severity, and associated clinical symptoms. Stem cell transplantation is the only curative therapy for the infantile malignant type, although alternative treatments, such as corticosteroids,...

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