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Original Article

Identification of a Calcium-activated Potassium Channel Gene Expressed in Rat Cardiac Myocytes

In Seung Park, Hyun-Kyu Jeon, Nam Su Kim, Youn Mo Ahn, Chul-Seung Park, Ha Baik

Clin Exp Pediatr. 2000;43(7):905-912. Published online July 15, 2000

Purpose : Calcium-activated potassium channels(KCa) may be involved in the transient outward current of the first phase of cardiac action potential. But it is still not clear whether cardiac myocytes express any KCa. We try to identify here the types of KCa expressed in rat caridac myocytes. Methods : We isolated total heart RNA from 50 rats(Spague-Dawley) and performed reverse transcription-polymerase chain reaction(RT-PCR) using specifically...

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