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Histiocytic Medullary Reticulosis: A case record and literatures review.

Kwang Ho Kim, Chi Ok Ahn, Byoung Soo Kim, Kir Young Kim, Dong Wha Lee, In Joon Choi

Clin Exp Pediatr. 1978;21(5):403-411. Published online May 31, 1978

Histiocytic medullary reticulosis was first described as a clinical and pathological entity by Scott and Robb-Smith in 1939. The clinical pictures include progressive pancytopenia, fever, wasting, lymphadenopathy, hepatosplenomegaly, jaundice and purpura. The outstanding morphological features of the disease is proliferation of histiocytes throughout the reticuloendothelial system with frequent leucoerythrophagocytosis. In spite of uniform clinical and fistologcal pictures verified by additional...

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