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Original Article
Effects of Vigabatrin on Pilocarpine-Induced Seizures in Immature Rats
Bo Ram Choe, In-Goo Lee, Kyung-Tae Whang
Clin Exp Pediatr. 2001;44(2):185-192.   Published online February 15, 2001
Purpose : Vigabatrin is a widely used antiepileptic drug that greatly increases whole brain γ- aminobutyric acid(GABA). But little is known about the anticonvulsant effect of vigabatrin on pilocarpine-induced seizures in the immature rats. This study was conducted to determine the effects of vigabatrin on pilocarpine-induced seizures in the immature rats. Methods : Six to eight day old Sprague-Dawley rats were...


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