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Original article

Hepcidin and other obesity-related factors affecting BNT162b2 response in children and adolescents over a 6-month period

Anthie Damianaki, Antonios Marmarinos, Margaritis Avgeris, Dimitrios Gourgiotis, Elpis-Athina Vlachopapadopoulou, Marietta Charakida, Maria Tsolia, Lydia Kossiva

Background: Obesity causes chronic inflammation and metabolic dysregulation of the immune response and increases an individual's susceptibility to severe infection.
Purpose: This study aimed to evaluate the effect of an increased body mass index (BMI), obesity-associated biomarkers, and habitual factors on immune responses following BNT162b2 vaccination in a pediatric population over a 6-month period. Methods: In this prospective, single-center cohort study, the...

DOI: https://doi.org/10.3345/cep.2026.01298 [Accepted]

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