Clinical and Experimental Pediatrics

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Original Article

Patient-independent automated pediatric seizure monitoring based on expert-labeled electrographic ictal data as core reference knowledge

Yoon Gi Chung, Jaeso Cho, Anna Cho, Hunmin Kim, Byung Chan Lim

Background: Automated seizure detection using scalp electroencephalography (EEG) is essential to the efficient monitoring of seizures in patients with epilepsy. However, patient-independent seizure detection remains challenging, primarily because of the inherent intersubject variability in EEG characteristics.
Purpose: We proposed a patient-independent seizure detection approach based on 1,604 single-channel electrographic focal-onset ictal EEG segments verified by epileptologists in patients with focal epilepsy. Methods:...

DOI: https://doi.org/10.3345/cep.2026.01011 [Accepted]

Case Report

A case of Menkes disease with unusual hepatomegaly

Go Un Jeong, Anna Cho, Hee Hwang, Yong Seung Hwang, Ki Joong Kim, Jong Hee Chae, Jeong Kee Seo

Clin Exp Pediatr. 2008;51(5):538-541. Published online May 15, 2008

Menkes disease is an X-linked recessive copper transport disorder characterized by neurological deterioration, connective- tissue damage, and abnormal hair growth. It is caused by the mutation of the ATP7A gene. This report describes a four- month-old boy with neurological symptoms typical of Menkes disease plus unusual liver involvement. He developed seizures at three months of age and exhibited hypotonia, cephalhematoma,...

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