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Enzyme Amplification, A Method Applied to Provide An ELISA for Studying Anti-Hib-Ps Antibodies in Children
Kyung Hyo Kim, Moon H. Nahm
Clin Exp Pediatr. 1997;40(2):173-180.   Published online February 15, 1997
Purpose : Enzyme immunoassay (EIA) is now a widely used technique. We have described the application of enzyme amplification (sensitive ELISA) in the field of immunoassays of pediatric population. There are two issues with the sensitive ELISA. First is that one can minimize the serum volume, an important concern for pediatricians. The second is the problem of background signal. We demonstrate that it...
Pertussis Antibodies in the Sera of Children after Acellular Pertussis Vaccination
Jeong Hwa Lee, Young Hee Ha, Ji Whan Han, Won Bae Lee, Kyong Su Lee
Clin Exp Pediatr. 1997;40(2):167-172.   Published online February 15, 1997
Purpose : The pertussis vaccines are divided into whole-cell vaccine and acellular vaccine. Purified component acellular pertussis vaccine, originally developed in Japan, has been used for primary immunization series in Korea since 1984. We performed this study to evaluate the prevalence of pertussis antibodies following vaccination with acellular pertussis vaccine. Methods : We randomized 80 children who were immunized according to vaccine schedules...
The Pelvic Changes of Patients with Down Syndrome in Korea
Jong Park, Kwan Cheol Oh, Kyoung Sim Kim, Ki Bok Kim
Clin Exp Pediatr. 1997;40(2):159-166.   Published online February 15, 1997
Purpose : Since Caffey et al. first described the anomaly in pelvis among the Down patients, decreased iliac and pelvic indexes have been helpful in diagnosing the syndrome. For Korean cases, however, no definitive data are available as yet, prompting us to evaluate the pelvic changes in Korean Down's patients. Methods : Subjected to this study were 68 children with Down's syndrome. As...
Dermatophagoides pteronissinus Specific IgG Subclasses according to Severity of Exercise Induced Asthma in Allergic Children
Young Mi Hong
Clin Exp Pediatr. 1997;40(1):110-116.   Published online January 15, 1997
Serum Thyroglobulin Concentrations in Congential Hypothyroidism
Jae Won Jung, Byun Churl Lee
Clin Exp Pediatr. 1997;40(1):104-109.   Published online January 15, 1997
The Association of Serum IGF-I, Growth Velocity, Fat Area and Muscle Area after Growth Hormone Treatment in Growth Hormone Deficient Children
Jeh-Hoon Shin, Ki-Joong Kim
Clin Exp Pediatr. 1997;40(1):97-103.   Published online January 15, 1997
Study on Hematologic Changes in the High School Students
Jeong-Ha Kwon, Jae-Kon Shim, Jae-Kook Cha, Do-Hyun Back, Hae-Sun Yoon
Clin Exp Pediatr. 1997;40(1):88-96.   Published online January 15, 1997
Serum Gastrin Levels in Relation to Helicobacter pylori Infection and Various Upper Gastrointesting Diseases
Hyun Young Kim, Ki Sup Chung
Clin Exp Pediatr. 1997;40(1):80-87.   Published online January 15, 1997
Clinical Presentations of Immotile Cilia Syndroms
Yong Han Sun, Myung Hyun Lee, Young Yull Koh, Je Geun Chi
Clin Exp Pediatr. 1997;40(1):69-79.   Published online January 15, 1997
Transcatheter Closure of Patent Ductus Arteriosus with the Rashkind PDA Occluder System
Hyoung Doo Lee
Clin Exp Pediatr. 1997;40(1):63-68.   Published online January 15, 1997
Tachycardia Induced Cardiomyopathy in Children
Jae Kon Ko, Young Hwee Kim, In Sook Park, Chang Yee Hong
Clin Exp Pediatr. 1997;40(1):55-62.   Published online January 15, 1997
The Effect of Salbutamol and Budesonide Inhalation Therapy in Infants with Bronchiolitis
Jae Hee Park, Jae Bum Lee, Kyong Tae Whang, Ji Hee Cho, Kyyong Og Ko, Yun Duk Yoo
Clin Exp Pediatr. 1997;40(1):45-54.   Published online January 15, 1997
Congenital Anomaly in Babies Born by In Vitro Fertilization and Embryo Transfer
Hye Young Kang, Myung Hyun Lee, Joong Hwan Choi, Jung Yun Choi
Clin Exp Pediatr. 1997;40(1):37-44.   Published online January 15, 1997
Time of First Defecation and Voiding in the Term and Premature Infants
Jong Yoo Lee, Jae Ock Park, Sang Mann Shin
Clin Exp Pediatr. 1997;40(1):29-36.   Published online January 15, 1997
Relationship of Ultrasonographic Findings and Neurologic Outcome in Infants with Birth Weight of Less 2,000gm
Seong Won Yang, Jung-Hwan Choi, Chong Ku Yun
Clin Exp Pediatr. 1997;40(1):21-28.   Published online January 15, 1997
Electroencephalogram in Phenylketonuria
Sang Hyun Kim, Eun Sook Suh, Dong Hwan Lee
Clin Exp Pediatr. 1997;40(1):13-20.   Published online January 15, 1997
The Clinical Study of Acute Poisoning in Children
Dae Kun Kim, Ki Cheol Choi, Eun Kyung Jung, Eun Seok Yang, Kyung Rye Moon
Clin Exp Pediatr. 1996;39(12):1753-1758.   Published online December 15, 1996
Purpose : Poisoning represents one of the most common accidents encountered by young children. Recently, mortality due to poisoning has gradually decreased, but the incidence has not decreased. We performed this study to compare the following factors during 1980's and 1990's : sex distribution, urban and rural distribution, causative substances. Methods : A clinical study was performed on 90 cases of acute poisoning who...
A Clinical Study on the Causes of Childhood Seizures According to the Age
Dong Wook Kim
Clin Exp Pediatr. 1996;39(12):1745-1752.   Published online December 15, 1996
Purpose : Although it is important to know the causes of childhood seizures according to the age, the clinical studies on this topic are rare in Korea. So, I would like to perform this clinical study to evaluate the frequencies of the age-related seizure causes in children. Methods : This study was retrospectively undertaken to evaluate the age and sex distribution,...
Evaluation of theIndications of Renal Biopsy in Children with Primary Nephrotic Syndrome
Seung Ju Lee
Clin Exp Pediatr. 1996;39(12):1736-1744.   Published online December 15, 1996
Purpose : Percutaneous renal biopsy in children with primary nephrotic syndrome(NS) contributed to establish the renal pathology and clinicopathological correlation. The most common minimal change lesion(MCL) was steroid sensitive and could be predicted by clinical and laboratory findings. It was uniformly agreed that most nephrotic children who were predicted as MCL, should receive an 8 week course of prednisolone before considering renal biopsy. Early indications...
Clinicopathological Study about Childhood Primary Nephrotic Syndrome Resistant to 4-week Daily Steroid Therapy
Jung Sue Kim, Il Soo Ha, Hae Il Cheong, Yong Choi
Clin Exp Pediatr. 1996;39(12):1729-1735.   Published online December 15, 1996
Purpose : Steroid-resistant nephrotic syndrome in children is difficult to manage and tends to progress to chronic renal failure. We studied clinicopathological correlations in primary nephrotic syndrome in children resistant to 4-week daily steroid therapy. Methods : Among children who had been admitted to Seoul National University Children's Hospital during the period between Oct. 1985 and Jul. 1995 and diagnosed as primary nephrotic syndrome, 87...
Myocardial Functions Estimated by Pulsed Doppler Echocardiography in Patientswith Chronic Renal Failure
Hyun June Huh, Byung Ho Choi, Myung Chul Hyun, Sang Bum Lee
Clin Exp Pediatr. 1996;39(12):1712-1728.   Published online December 15, 1996
Purpose : The objectives of this study were to estimate myocardial functions in patients with chronic renal failure by pulsed Doppler echocardiography, and investigate correlation between Doppler and disease parameters. Methods : We studied 13 patients with chronic renal failure whose creatinine clearance rate less than 25ml/min. Using pulsed Doppler echocardiography with curve following method, we measured peak velocity, mean velocity, velocity-time integral and peak...
The Risk Factors related to Recurrent Intussusception by Ultrasonography
Eun sun Yoo, Jeong Wan Seo, Seung Joo Lee
Clin Exp Pediatr. 1996;39(12):1707-1716.   Published online December 15, 1996
Purpose : We investigate the risk factors of recurrence after first intussusception. Methods : We have studied the relationship of the clinical features and ultrasonographic findings and the risk of recurrent intussusception in 97 patients with reduced intussusception including 22 recurrent intussusception who admitted at the department of pediatrics at Ewha Womans University Mok-dong hospital from September 1993 to Feburary 1996. Results...
Reappraisal of the Efficacy of Measles Vaccination
Sung Ho Cho, Hyo Geun Ju, Chang Hee Cho, Young Youn Choi, Jae Suk Ma, Tae Joo Hwang
Clin Exp Pediatr. 1996;39(12):1700-1706.   Published online December 15, 1996
Purpose : Measles is one of the most highly communicable infectious disease, but has become a rare disease with the widespread use of vaccine. Recently, however, resurgence of the disease in school aged or adolescents who had received the vaccine before or at the 15 month warrants reappraisal of the efficacy of the vaccination. The purpose of this study was...
Etiology and Clinical Features of Acute Viral Lower Respiratory Tract Infection in Apparently Healthy children
Song Yi Nah, Jeong Yun Hong, Eun Hwa Choi, Hoan Jong Lee
Clin Exp Pediatr. 1996;39(12):1690-1699.   Published online December 15, 1996
Purpose : Acute lower respiratory tract infections(LRIs) are an important cause of pediatric morbidity and mortality. Causes of acute LRI in infants and children include bacteria, mycoplasma and respiratory viruses. Understanding of the epidemiology, etiology and clinical features of acute viral LRI is essential to improve the methods of prevention, diagnosis and management of these infections. Methods : Viral etiologic agents and clinical features of...
Relationship between Complications of Mycoplasma Pneumonia and Titers of Cold Agglutinin and Mycoplasma Antibody in Children
Sung Soo Rim, Myung Hyun Cho, Byung Min Moon, Kyoung Sim Kim, Kibok Kim
Clin Exp Pediatr. 1996;39(12):1680-1689.   Published online December 15, 1996
Purpose : To assess the relationship between the complications of mycoplasma pneumonia and titers of cold agglutinin and mycoplasma antibody in children. Methods : 120 cases of mycoplasmal pneumonia in children who were admitted to the Pediatric Department of Kwangju Christian Hospital between June 1993 and May 1994 were analyzed. Results : 1) The peak incidence of age was between 2 and...
TheAnalytic Review of Standard Growth Valuein School-Age Children in Seoul
Joo Young An, Jin Seop Kang, Young Jin Hong, Don Hee Ahn, Sung Jae Suh
Clin Exp Pediatr. 1996;39(12):1669-1679.   Published online December 15, 1996
Purpose : It hasn't been developed a new standard growth value for children in Korea since 1985. This study was designed to compare the difference of standard growth value of height, weight and chest circumference for school-age children in Seoul between 1985 and 1994. Methods : Height, weight and chest circumference were measured in 6,308 students, aged 6-17 years, of 12...
Study of Epstein Barr Virus Antibodies in Patients with Kawasaki Disease
Dong Hee Shin, Kyung Hyo Kim, Young Mi Hong, Gyung Hee Kim
Clin Exp Pediatr. 1996;39(11):1603-1610.   Published online November 15, 1996
Purpose : The etiology of the Kawasaki disease remains unclear, many strong clinical and epidemiologic characteristics suggest an infectious etiology. However, conventional bacterial and viral cultures and extensive serologic studies have not revealed a consistent causative agent. Thus we studied the Epstein Barr virus(EBV), one of the most important pathogens, to access the association between the EBV and Kawasaki disease. Methods : Seventy-two patients with...
The Characteristics of Insulin-like Growth Factor Binding Protein-3(IGFBP-3) in Serum; The Diagnostic Utility of IGFBP-3 in Growth Hormone Deficiency
Ki-Joong Kim, Jeh-Hoon Shin, Young-Ik Lee
Clin Exp Pediatr. 1996;39(11):1594-1599.   Published online November 15, 1996
Purpose : For diagnosis of growth hormone(GH) deficiency in short stature, peak growth hormone levels after pharmacologic stimulation are usually used. In this study, we measured serum IGFBP-3, which is a major binding protein in serum and is considered to be GH-IGF-I axis dependent, levels by radioimmuno assay(RIA) in sera from normal short stature(NSS) children, and patients with GH deficiency children to clarify the...
Diagnostic Value of 99mTc-DMSA Renal Scan for Early Diagnosis of Acute Pyelonephritis in Children with Febrile Urinary Tract Infection
Soo Ja Hwang, Eun Ae Park, Jeong Wan Seo, Seung Joo Lee, Sun Whan Lee
Clin Exp Pediatr. 1996;39(11):1586-1593.   Published online November 15, 1996
Purpose : For prevention of renal scar, early diagnosis and treatement of acute pyelonephritis are important in children with febrile urinary tract infection. But it has been difficult to differentiate acute pyelonephritis from lower urinary tract infection. We have performed this study to evaluate the diagnostic value of 99mTc-DMSA renal scan and to clarify the relationship among acute pyelonephritis, vesico-ureteral reflux and renal scar. Methods...
The Effect of Allopurinolon the Ischemia-reperfusion RenalInjury in Young Rats
Seung Joo Lee
Clin Exp Pediatr. 1996;39(11):1576-1585.   Published online November 15, 1996
Objective : Oxygen free radicals has been reported to be the critical cellular mediators of experimental ischemia-reperfusion renal injury. We examined the protective effect of allopurinol (an xanthine oxidase inhibitor) on the renal damage by reperfusion in the ischemic rat kidney. Methods : To induce renal ischemia, the Sprague-Dawley rats(weight 70-80g) were placed in a sealed 5L jar with 8% O2-92% N2 gas mixture...
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