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Original Article
A Study on Clinical Application of Harada's Scoring Method to Kawasaki Disease - Suggesting the revision of the criteria for IVGG treatment of KD in Korea -
Byoung Kil Han, Hyong Shin Lee, Hong Ryang Kil, Heon-Seok Han, Jae Ho Lee, Young Hun Chung
Clin Exp Pediatr. 1997;40(4):539-548.   Published online April 15, 1997
Purpose : We performed a study on clinical benefits of Harada's scoring method, problems of present criteria and requirement of the revision of that criteria for intrvenos γ-globulin(IVGG) treatment of Kawasaki disease(KD) in Korea. Methods : The patients of 104 cases who visited to Department of Pediatrics of Chungnam National University Hospital and diagnosed as KD were objective group. We classified the...
An Electroencephalographic Study of Febrile Convulsion in Childhood
Jong Woo Shin, Chang Ok Soh, Jin Young Jeong
Clin Exp Pediatr. 1997;40(4):531-538.   Published online April 15, 1997
Purpose : Febrile convulsion is most common neurologic disorder in childhood, which benign course but transition to epilepsy is not certain. This study was carried out to reveal the usefulness of electroencephalography of febrile convulsion in childhood. Methods : Electroencephalography (EEG) was performed on 116 children who visited the department of Pediatrics, Haesung hospital from November 1992 to December 1994 due...
Outcome after Treatment of Retinoblastoma
Hyoung Soo Choi, Ki Woong Seong, Jae Kyung Lee, Kyung Ha Yoo, Hee Young Shin, Young Suk Yu, Hyo Seop Ahn
Clin Exp Pediatr. 1997;40(4):519-530.   Published online April 15, 1997
Purpose : Current treatment in retinoblastoma aims to save life and preserve useful vision by using combined modality therapy. This study was performed to determine the outcome after treatment of retinoblastoma. Methods : Medical records of all cases of retinoblastoma seen at Seoul National University Children's Hospital from September 1986 to April 1995 were reviewed. During this period, the treatment method...
Recent Trend of Increasing Proportion of Interventional Catheterization in Congenital Heart Disease
Sang Yup Lee, Mi Jung Kang, Eun Jung Bae, In Seung Park, Woo Sup Kim, Se Jung Sohn, Seong Ho Kim
Clin Exp Pediatr. 1997;40(4):512-518.   Published online April 15, 1997
Purpose : The proportion of interventional catheterization in congenital heart disease is being increased in Korea, especially in Sejong Heart Institute, so we performed statistical analysis on the cardiac catheterization cases. Methods : Total 233 cases of congenital heart disease confirmed by cardiac catheterization at the Sejong Heart Institute between Jaunary 1995 and June 1995 were analyzed retrospectively. Results : 1) The...
Fixed Subaortic Stenosis in Children
Eun Jin Choi, Byung Ho Choi, Myung Chul Hyun, Sang Bum Lee
Clin Exp Pediatr. 1997;40(4):505-511.   Published online April 15, 1997
Purpose : This study attempted to describe the Doppler and two-dimensional echocardiographic features of fixed subaortic stenosis, the de novo occurrence and progression of this lesion and to review its etiology, treatment and course. Methods : We studied 17 patients of fixed subaortic stenosis who, between Jan. 1993 and Jan. 1996, ware diagnosed by echocardiographic examination at Kyungpook National University Hospital....
Effect of Nebulized Steroid(Budesonide) and Parenteral Steroid(Dexamethasone) on Children with Croup
Seon Mee Ahn, Jung Ae Sohn, Chul Zoo Jung, Dong Jin Lee, Young Hwan Lee, Yong Hoon Park
Clin Exp Pediatr. 1997;40(4):497-504.   Published online April 15, 1997
Purpose : This prospective study was conducted to evaulate the effect of nebulized steroid(budesonide) and parenteral steroid(dexamethasone) on chidren with croup. Methods : Twenty nine infants and children(6months-5years of age) admitted to hospital with croup were randomly assigned to receive either 1mg(4ml) of nebulized budesonide(17 patients) or 0.6mg/kg intramuscular injection of dexamethasone sodium phosphate(12 patients). Total croup score, heart rate...
Conversion Rates of Tuberculin Test according to BCG Vaccination Methods
Woo Sung Kim, Chang Hwi Kim, Dong Hwan Lee, Sang Mann Shin
Clin Exp Pediatr. 1997;40(4):489-496.   Published online April 15, 1997
Purpose : Tuberculosis, a major public health problem, is an important cause of childhood morbidity and mortality in developing countries. To decline the tuberculosis morbidity rate, active BCG vaccination is performed worldwide. Recently percutaneous multiple puncture technique of BCG vaccination was introduced and used because of side effects of intradermal BCG vaccination such as scar, local ulceration, regional suppurative lymphadenitis....
Relationship between Antistreptolysin O Titer and Number of Colonies from Throat Swab Culture Plate in Group A Beta-hemolytic Streptococcal Carriers and Normal School Children
Sungho Cha
Clin Exp Pediatr. 1997;40(4):480-488.   Published online April 15, 1997
Purpose : To know the true carrier rate and the immunologic responses(antistreptolysin O :ASO) to beta-hemolytic streptococci which obtained from normal school children with or without carrying streptococci. And to study the clinical meaning of the number of organisms found in culture. Methods : One hundred ninty-eight first grade of elementary school children were included. I obtained throat swab culture from...
Plasma Fibronectin Concentration in the Premature,Fullterm Neonates and Infants
Hyun Joo Lee, Kyung Hyo Kim, Gyoung Hee Kim
Clin Exp Pediatr. 1997;40(4):473-479.   Published online April 15, 1997
Purpose : Plasma fibronectin has important role in the inflammatory response as non-specific opsonin and host defense. Plasma fibronectin concentration is different according to age and presence of infection. We performed this study to evalulate plasma fibronectin concentration in the healthy preterm, term neonates and infants and how that correlate with gestational age and birth weight and increased CRP concentration....
Development of Approximate Entropy of Fetal Heart Rate Varibility during Normal Pregnancy
Myung Kul Yum, Jung Hye Hwang, Moon Il Park
Clin Exp Pediatr. 1997;40(4):464-472.   Published online April 15, 1997
Purpose : The approximate entropy of heart rate variability has recently been used as a tool in evaluating cardiovascular health and physiology and in diagnosing pertubated physiologic status, by quantifying the irregularity and the pattern of the heart rate variability. Therefore approximate entropy of the fetal heart rate variability will be used as an important tool in studying the fetal...
A Study on Menarchel Age and Monthly Incidence of School Girls in Ansan
Hyung Seok Kim, Jae Yong Kim, Young Kyu Shin, Sang Hee Park, Young Chang Tockgo
Clin Exp Pediatr. 1997;40(4):458-463.   Published online April 15, 1997
Purpose : Menarche is an important life event, making the transition from childhood to early womanhood. It is a significant physical and physiological event that adolescent girls feel sexual identity and it affects on psychological development. The onset of menstruation is considered a practical indication of sexual maturity in girls. On a population level, mean menarcheal age is considered to...
Clinical Study of Symptoms and Various Anomalies of Patients with Joubert Syndrome
Hang Bo Jeong, Se Hee Hwang, Ki Joong Kim, Yong Seung Hwang, Seung Cheol Kim, In-One Kim
Clin Exp Pediatr. 1997;40(3):385-392.   Published online March 15, 1997
Purpose : Joubert syndrome is known tobean autosomal recessive disorder characterized by cerebellar vermian dysgenesis with many symptoms and variety of other malformations. We studied the relevant symptoms and various malformations of seven patients diagnosed as Joubert syndrome at our institution. Methods : Seven children with cerebellarvermian dysgenesis consistent with Joubert syndrome were included in ourstudy. Each child was diagnosed at the Seoul National University Children's...
A Clinical Study of Congenital Urinary Tract Anomalies in Children
Mi-Young Han, Seong-Ho Cha, Byong-Soo Cho, Jin-Il Kim, Yung-Tae Ko
Clin Exp Pediatr. 1997;40(3):375-384.   Published online March 15, 1997
Purpose : A study was done to assess the incidence, clinical characteristics of urinary tract anomalies for decreasing urinary tract morbidity. Methods : We review 98 cases of anomaly of urinary tract who were admitted Kyung Hee University Hospital between 1986 and 1995. We analyzed incidence and associated anomalies, associated diseases and treatment modalities. Results : 1) It was composed of 45 cases(45%) of renal...
Subclavian Catheterization in the Pediatric Patients
Seung Hee Lee, Sung Ho Cho, Keun Mo Kim, Chan Jong Kim, Hoon Kook, Tai Ju Hwang
Clin Exp Pediatr. 1997;40(3):368-374.   Published online March 15, 1997
Purpose : Central venous catheters are used to deliver antibiotics, chemotherapeutic agents, and parenteral nutrition for a extended period of time as well as to draw samples in immunocompromised patients to minimize the discomfort with sampling and the risk of introducing infections. Hickman/Broviac catheters or implantable devices have been used in pediatric patients. This study is aimed to evaluate the safety and clinical efficacy of...
Prophylactic Treatment of Anemia of Prematurity with Recombinant Human Erythropoietin and High Doses of Iron
Young Ho Lee, Ahn Hong Choi, Soon Yong Lee, Jeong Sook Park, Bong Keun Choi, Hyoung Shim Chang
Clin Exp Pediatr. 1997;40(3):361-367.   Published online March 15, 1997
Purpose : We conducted randomized study to determine whether high doses(6mg/kg/ day) of iron would exert a more supplemental effect than low doses(3mg/kg/day), and which regimen of recombinant human erythropoietin(rHuEPO) and iron would be more beneficial in the prophylactic treatment of anemia of prematurity. Methods : We randomly assigned 38 sick premature infants who were more likely than symptom-free premature infants requiring erythrocyte transfusions for...
Whole blood and Plasma Vitamin C Concentrations of Elementary School Children in Chinju
Yoon-Ok Kim, Myoung-Bum Choi, Youn-Kyeong Cho, Sun-Kyeong Sin, Song-Ja Kim, Hyang-Ok Woo, Seoung-Hwan Kim, Hee-Shang Youn, Seon-Ju Kim, Kook-Young Maeng, Gyung-Hyuck Ko, Seung-Chul Baik, Woo-Kon Lee, Myung-Je Cho, Kwang-Ho Lee
Clin Exp Pediatr. 1997;40(3):352-360.   Published online March 15, 1997
Purpose : Recommended dietary allowance of vitamin C was determined on the basis of preventing the scurvy without considerations of the important function of the vitamin C as a first line antioxidant. So we measured the whole blood and plasma vitamin C concentrations of the contemporay healthy elementary school children in Chinju for the establishment of the optimal daily vitamin C...
Experience of Stent Implantation in Branch Pulmonary Artery Stenosis of the Congenital Heart Diseas
Yong Soo Yun, Eun Jung Cheon, Ho Sung Kim, Chung Il Noh, Jung Yun Choi
Clin Exp Pediatr. 1997;40(3):343-351.   Published online March 15, 1997
Purpose : Branch pulmonary artery stenosis remains a clinically challenging lesion. Results of surgical angioplasty are rarely rewarding, and balloon angioplasty is not uniformly successful. So, endovascular stent has been applied recently to these lesions. But this new modality has not been full yevaluated. The aim of this study is to evaluate the short-term result of stent implantation in postoperative branch pulmonary artery stenosis. Methods :...
Effects of Nebulized Budesonidein the Treatment of Patients with Mild to Moderate Croup
Yun Jong Kang, Chan Young Park, Soo Young Choi, Yeun Jung Jung, Jin Keun Chang
Clin Exp Pediatr. 1997;40(3):336-342.   Published online March 15, 1997
Purpose : Dexamethasone intramuscular injection and oral prednisolone have been known to be effective in the treatment of croup. The aim of this study was to determine whether nebulized budesonide leads to clinically important improvement in respiratory symptoms within four hours for child with mild to moderate croup. Methods : Patients with croup visited to the department of Pediatrics, Han Il General Hospital...
Effect of Meconium Components on Haemophilus influenzae Growth by Surfactan
Min Hee Kim, Sang In Chung
Clin Exp Pediatr. 1997;40(3):327-335.   Published online March 15, 1997
Purpose : Meconium is a complex mixture with a potential variable composition, it is difficulty to determine which components of meconium are responsible for the surfactant inhibition. We previous reported that Surfactant-TA and Exosurf almost completely inhibited the growth of Haemophilus influenzae at the concentration of 100% without apparent difference in the efficiency.In this study, We have determined the effect of...
Risk factors for Pulmonary Interstitial Emphysema(PIE) in Mechanically Ventilated Neonates with Hyaline Membrane Diseas
Shin Won Yoon, Chul Lee, Jeong Nyun Kim, Ran Namgung, Dong Gwan Han, Myung Joon Kim
Clin Exp Pediatr. 1997;40(3):318-326.   Published online March 15, 1997
Purpose : Pulmonary interstitial emphysema(PIE) is a common and serious complication of mechanical ventilation in infants with hyaline membrane disease. This abnormal collection of gases has two basic roentgenographic features; linear and cyst-like radiolucencies. High positive inspiratory pressure was found to be the most significant parameter associated with development of fatal pulmonary interstitial emphysema. Without prompt conservative management such as lowering peak inspiratory...
The State of Smoking and Alcohol Usein Korean Adolescent
Gi Chan Lee, Young Joon Kim, Young Kyoo Shin, Baik-Lin Eun, Sang Hee Park, Young Chang Tockgo
Clin Exp Pediatr. 1997;40(3):307-317.   Published online March 15, 1997
Purpose : Recently, smoking and alcohol use in adolesecnt have increased and it has been a social issue in Korea.This study was performed to understand the state of smoking and alcohol use in Korean adolescents, and to make abasic data for education of them. Methods : This study was carried in 1994.3,360 students in 13 schools aged from 13 to 18 were enrolled in this...
Characteristics and Follow-Up of Bronchial Hyperresponsiveness in Cough Variant Asthma
Jeong-Ho Kim, Jung-Yeon Shin, Soo-Jong Hong
Clin Exp Pediatr. 1997;40(2):240-248.   Published online February 15, 1997
Purpose : Cough variant asthma is characterized as a persistent, nonproductive cough with minimal or no wheezing and dyspnea. Cough variant asthma can be overlooked or misdiagnosed because it is a common problem amongst all ages that frequently is unrecognized. The patho-physiology of cough variant asthma is still unclear. Methods : To characterize the pathophysiological abnormalities of cough variant asthma, bronchial provocation tests with methacholine...
A Clinical Study on Back Pain after Lumbar Punctureon Aseptic Meningitis
Jai Young Kim, Won Hee Kim, Sung Wook Jung, Sung Won Kim
Clin Exp Pediatr. 1997;40(2):233-239.   Published online February 15, 1997
Purpose : This study is to assess the occurence rate, severity, and duration of the back pain after lumbar puncture. Methods : The occurence rate, severity and duration of the back pain that developed after lumbar puncture were recorded prospectively in patients with aseptic meningitis who had been admitted to the department of Pediatrics, St. Benedict Hospital in Pusan, from May 1993 to July...
A Study on thePredisposing Factors to Complex Febrile Convulsion
Ge Woo Yi, Dong Wook Kim
Clin Exp Pediatr. 1997;40(2):225-232.   Published online February 15, 1997
Purpose : Febrile convulsion is classified as simple or complex type, the latter being characterized by frequent recurrence of febrile convulsion itself and progression to epilepsy. This study was performed to seek the predisposing factors to complex febrile convulsion. Methods : This study was retrospectively undertaken to review medicalrecords of 472 children under 15 years of age with febrile convulsions, who were...
The Hematologic Effect of Antiepileptic Drug
Dae Hun Pee, Young Kwan Park, Baik Lin Eun, Sang Hee Park, Soon Kyum Kim
Clin Exp Pediatr. 1997;40(2):217-224.   Published online February 15, 1997
Purpose : There have been controversies on the hematologic effects of antiepileptic drugs according to the mono or combined antiepileptic therapy. We evaluated the hematologic changes of the patients who have been taking antiepileptic drugs for more than 4 months and compared the changes of these values according to the mono or combined therapy. Methods : From May,1989 to April,1995, we had examined the blood...
Abnormal Electrogastrography and Gastric Emptying Time in Patients with Cyclic Vomiting Syndrome during Symptom Free Interval
Nam Seon Beck
Clin Exp Pediatr. 1997;40(2):209-216.   Published online February 15, 1997
Purpose : Cyclic vomiting syndrome is characterized by repeated, unpredictable, explosive and unexplained bouts of vomiting and recur after intervals of uncertain length. In the absence of either known etiology or pathogenesis, deciphering the mystery of cyclic vomiting syndrome presents us with a daunting clinical challenge. As we seek to understand this mysterious vomiting disorder of unknown etiology and pathogenic mechanism,...
Recurrent Abdominal Pains:A Field Survey of 1,783 School Children in Seoul
Yong Hwan Cho, Byung Duk Seo, Yong Joo Kim, Nam Su Kim, Hahng Lee
Clin Exp Pediatr. 1997;40(2):199-208.   Published online February 15, 1997
Purpose : We investigated the occurrence rate of recurrent abdominal pain(RAP) in general population of elementary school children, accompanied symptoms, symptomaggravating factors such as emotional stresses, food and personality characters, which time of day the pain develops and whether they visited hospital for RAP. Methods : From 1995. 4. 27. to 1995. 5. 12. questionnaires were given to the parents of 1,783...
Serum EosinophilCationic Protein Levelsin Patients with Recurrent Croup
Moon Kil Bahng, Do Yoon Lee, Mee Kyung Namgoong, Jong Soo Kim
Clin Exp Pediatr. 1997;40(2):194-198.   Published online February 15, 1997
Purpose : Most patients suffer from croup only once in a life time. However, a small group of patients suffer from it several times. A type of croup from which they suffer more than 3 times is called recurrent croup. The cause of recurrent croup has not been clearly described, but in recent years the allergic reaction is considered as a...
Pulmonary Air Leak Syndrome Associated with Respiratory Diseasein Infancy and Childhood
Hae Kyung Lee
Clin Exp Pediatr. 1997;40(2):189-193.   Published online February 15, 1997
Purpose : Pneumothorax, pneumomediastinum and subcutaneous emphysema rarely complicate pediatric respiratory disease such as bronchial asthma, bronchiolitis, bronchopneumonia. But physicians unfamiliar with natural history of these complications may feel that surgical intervention is necessary. So this study was done to to recognize the pulmonary air leak syndrome associated with respiratory disease in infancy and childhood. Methods : I reviewed retrospectively the medical...
Changes of Anti-H.influenzae Type b IgG in the Sera of Korean Infants and Children after Birt
Jong Man Park, Keoung Hie Moon, Kyung Mee Lee, Sun Jun Kim, Soo Chul Cho, Jung Soo Kim
Clin Exp Pediatr. 1997;40(2):181-188.   Published online February 15, 1997
Purpose : Most of invasive Haemophilus influenzae diseases occur in children under 5 years of age, and are due almost exclusively to type b strain. Although antibodies to several surface antigens of H.influenzae play a role in conferring immunity, antibody to the type b capsular polysaccharide appeared to have the most important protective functions. However, the antibody response to vaccines or natural...
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