• Search
  • Advanced Search

Original article

  • HOME
  • ARTICLE CATEGORY
  • Original article
Article category
Original Article
Risk Factors for Cardiovascular Disease in Obese Children
Su Jin Cho, Se Jin Park, Il Tae Hwang, Young Mi Hong
Clin Exp Pediatr. 2001;44(5):493-500.   Published online May 15, 2001
Purpose : Obesity is known to be associated with complications such as hypertension, dyslipidemia, and insulin resistance. The importance of insulin resistance and hyperinsulinemia have been emphasized in obesity. Homocysteine is an emerging important risk factor for cardiovascular disease in adult, but there are less reports about homocysteine in children. Several risk factors such as blood pressure, lipid profiles, serum...
Clinical Evaluation of Hypoglycemic Symptoms Reported by Children with Insulin-dependent Diabetes Mellitus and by Their Parents
Byeong Eul Lee, Hwa Young Park, Cheong Mi Cheon, Eun Kyeong Kwon, Seung Mee Song, Jung Sim Kim, Dong Kyu Jin
Clin Exp Pediatr. 2001;44(4):450-455.   Published online April 15, 2001
Purpose : The following study has been carried out to find the symptoms of hypoglycemia and the symptoms of transient focal neurologic deficit, which were complained by insulin dependent diabetes mellitus patients and their parents. Methods : The subjects of this study were 16 insulin dependent diabetic patients who were admitted to the pediatric department of Samsung Medical Center. From the...
Clinical Characteristics of Williams Syndrome
Choong Ho Shin, Ho Sung Kim, Sei Won Yang, Jung Yun Choi
Clin Exp Pediatr. 2001;44(4):443-449.   Published online April 15, 2001
Purpose : Williams syndrome(WS) is an autosomal dominant disorder resulting from a submicroscopic deletion of contiguous genes on the long arm of chromosome 7. We evaluated the physical, neurodevelopmental, and behavioral characteristics of children and adults with WS confirmed by fluorescence in situ hybridization. Methods : The clinically suspicious twelve cases with cardiac anomaly were confirmed as WS with fluorescence in...
Experssion of the NR2A and 2B Subunits of N-Methyl-D-aspartate Receptors in Hypoxic Neonatal Rat Hippocampus
Jong Su Lee, Dong Seok Lee, Jung hyun Park, Il Soo Moon, Bok Hyun Ko, Yong Wook Jung
Clin Exp Pediatr. 2001;44(4):433-442.   Published online April 15, 2001
Purpose : The developing brain has been reported to be extremely susceptible to toxicity of ischemia and/or hypoxia during a restriced developmental period. Hippocampal neuronal cell death is a typical type of perinatal hypoxic brain lesion and often coexists with other forms of cerebral hypoxic injuries. In the present study, we examined whether transcriptional changes of NR2A and NR2B subunits...
Significance between Ultrasonographic and Operative Findings in Hypertrophic Pyloric Stenosis
Jun Ho Kim, Woo Taek Kim, Byeong Ook Jung
Clin Exp Pediatr. 2001;44(4):426-432.   Published online April 15, 2001
Purpose : The diagnosis of hypertrophic pyloric stenosis(HPS) can be made by clinical manifestations and upper gastrointestinal(UGI) series in most cases. Recently, the ultrasonogram(US) is a more accurate and reliable method for the diagnosis of HPS in early stage. Methods : We retrospectively studied 27 HPS patients confirmed surgically from January 1999 to March 2000. We reviewed clinical histories and physical and laboratory findings....
Ventricular Inhomogeneity and Beat-to-beat QT Interval Variability after Surgical Repair of Tetralogy of Fallot
Su-Hyun Kim, Myung-Kul Yum, Nam-Su Kim, Chang-Ryul Kim, Chul-Burm Lee, Chung-Ill Noh, Hee-Soo Kim
Clin Exp Pediatr. 2001;44(4):418-425.   Published online April 15, 2001
Purpose : The object of this study is to determine whether QT interval variability in patients with postoperative tetralogy of Fallot increases. Methods : We enrolled 41 patients who had total correction of tetralogy of Fallot, and 31 healthy controls. They were 6-12 years old. Patients were divided into 2 groups : arrhythmia-positive patients(n=10) who had ventricular premature contractions more than...
The Weaning Method of Inhaled Nitric Oxide
Hyun Woo Lee, Jae Woong Lee, Sung Yeul Hyun, Ha Chang Lee, Chul Hyun Park, Kook Yang Park, Hyeon Su Yoo, Kyung Cheon Lee, Young Jin Jang
Clin Exp Pediatr. 2001;44(4):413-417.   Published online April 15, 2001
Purpose : Inhaled nitric oxide(iNO) is an excellent method for the postoperative pulmonary hypertension in congenital heart disease. But more detailed care is needed because of the development of rebound pulmonary hypertension after NO withdrawal. We performed this study in order to discontinue the iNO successfully by way of presenting the adequate weaning and supplying methods. Methods : Between January, 1998...
Antibody Levels and Opsonophagocytic Function to S. pneumoniae 19F Capsular Polysaccharide
Kyung Hyo Kim, Ju Young Seoh, Moon Kook Park
Clin Exp Pediatr. 2001;44(4):405-412.   Published online April 15, 2001
Purpose : The increasing prominence of pneumococcal infections and of antimicrobial resistance has emphasized the need for a effective vaccine to reduce the risk of pneumococcal disease in childhood. To study the antibody response of pneumococcal vaccine, we compared the concentration and opsonophagocytic capacity of antibodies to the capsular polysaccharide of S. pneumoniae serotype 19F in sera from healthy adults...
The Effect of rhG-CSF and rhGM-CSF on Expression of Fcγ Receptors and β2 Integrin and Respiratory Burst Function in Human Granulocytes
Kyung Hyo Kim, Kyung Ha Ryu, Moon Kook Park
Clin Exp Pediatr. 2001;44(4):397-404.   Published online April 15, 2001
Purpose : Receptors for the Fc of IgG(FcγR) and a β2 integrin molecule, CD11c/CD18 are important in clearance of microbes by granulocytes. We performed an in vitro study on the effect of recombinant human granulocyte colony-stimulating factor(rhG-CSF), or granulocyte-macrophage colony-stimulating factor(rhGM-CSF) on the expression of FcγR II, FcγR III, CD11c and CD18 and respiratory burst function of granulocytes. Methods : Peripheral...
A Survey on the Factors of Breast Feeding Failure Related to the Role of Medical Personnels
Min Jung Cho, Cheong Mi Cheon, Jeong Kyung Seo, Son Moon Shin
Clin Exp Pediatr. 2001;44(4):389-396.   Published online April 15, 2001
Purpose : The reasons for breast feeding failure within the first month of birth were related to inappropriate handling of problems in breast feeding. We investigated common reasons for the failure during the neonatal period and assessed medical personnels` attempts to solve them. Methods : We conducted a survey with a prepared questionnaire on one-hundred-twenty mothers who failed in breast feeding...
MMR Immunization Rate and Related Factors - Findings from Repeated Surveys(1996, 1999) on Elementary School Students in Kyonggi Province, Korea -
Moran Ki, Moynghee Kim, Young-Jeon Shin, Boyoul Choi
Clin Exp Pediatr. 2001;44(4):375-388.   Published online April 15, 2001
Purpose : This study was carried out to obtain the immunization rate of MMR, and to know the related factors. Methods : Subjects of the study were 3,364 students of 8 elementary schools of Kyonggi province. Surveys accompanied with questionnaires were conducted in 1996 and 1999, respectively. Results : The salient features of the findings were as follows : The immunization rate...
Age-related Results of Skin Prick Test in Children with Allergic Asthma
Jae Sung Son, Yang Park, Yong Han Sun, Myung Hyun Lee, Young Yull Koh
Clin Exp Pediatr. 2001;44(2):193-199.   Published online February 15, 2001
Purpose : Skin reactivity to different allergens may vary with age, since the degree and type of sensitization may be related not only to genetic factors but also to the intensity and duration of exposure to the allergens. The aim of this study was to evaluate profile of sensitization to airborne allergens according to age in children with allergic asthma. Methods...
Effects of Vigabatrin on Pilocarpine-Induced Seizures in Immature Rats
Bo Ram Choe, In-Goo Lee, Kyung-Tae Whang
Clin Exp Pediatr. 2001;44(2):185-192.   Published online February 15, 2001
Purpose : Vigabatrin is a widely used antiepileptic drug that greatly increases whole brain γ- aminobutyric acid(GABA). But little is known about the anticonvulsant effect of vigabatrin on pilocarpine-induced seizures in the immature rats. This study was conducted to determine the effects of vigabatrin on pilocarpine-induced seizures in the immature rats. Methods : Six to eight day old Sprague-Dawley rats were...
The Relationship between Change of Cardiac Function and Systemic Oxygen Consumption according to the Dose of Dopamine in the Rabbit
Hee Ju Park, Seok Ho Yoon, Bong Seok Choi, Jung Hwoi Cho, Ku Tae Kim, Sun Young K, Sang Ook Nam, Bok Luel Lee
Clin Exp Pediatr. 2001;44(2):177-184.   Published online February 15, 2001
Purpose : We'd like to know the relationship between the changes of cardiac function and systemic O2 consumption according to the increasing dose of dopamine. Methods : Ten rabbits(from 2kg to 2.8kg) were used in this experiment. Anesthesia was induced with intraperitoneal pentobarbital sodium(35mg/kg) and tracheostomy was done. It was maintained by ventilation with a mixture of 1-3% halothane and 67-69%...
Study for Balloon Aortic Valvuloplasty in Congenital Aortic Stenosis
In Seung Park, Do Jun Cho, Mi Young Han, Jae Young Lee, Soo Jin Kim, Mee-Hye Oh, Eun Jung Bae, Seong Ho Kim
Clin Exp Pediatr. 2001;44(2):167-176.   Published online February 15, 2001
Purpose : The aims of this study are to investigate the results of balloon aortic valvuloplasty (BAV) in congenital aortic stenosis(CAS) and, especially, to compare the results between BAV performed before two months of age(Group A) and BAV after two month of age(Group B). Methods : From January 1993 to June 2000, 14 patients who were diagnosed as CAS were treated...
Analysis of Malnutrition in Children with Congenital Heart Disease
Jeoung Eun Kim, Bo Hwa Choi, Kyung Mo Kim, Jae Kon Ko, Dong Man Seo
Clin Exp Pediatr. 2001;44(2):161-166.   Published online February 15, 2001
Purpose : Malnutrition and failure to thrive have long been recognized as common systemic consequences of congenital heart disease(CHD). But there is little data about the prevalence and severity of malnutrition with CHD in Korea. We designed this study to determine the prevalence of malnutrition among hospitalized children with CHD. Methods : We reviewed 100 hospitalized children with CHD who were...
Diagnostic Assessment of Pulmonary Atresia with Ventricular Septal Defect; Comparison of Echocardiogram with Cardiac Angiography
Jung Yun Choi, Jeong Jin Yu, Soo Jung Kang, Jae Seong Son, Young Mee Seo, Jin Young Song, Ho Sung Kim, Eun Jung Bae, Chung Il Noh, Yong Soo Yun
Clin Exp Pediatr. 2001;44(2):154-160.   Published online February 15, 2001
Purpose : Patients with pulmonary atresia with ventricular septal defects(PAVSD) have been a formidable surgical challenge. The source of pulmonary blood flow and vascular architecture are important in managing the surgical process. This study aimed to evaluate the usefulness of echocardiography in this process. Methods : This study was prospectively designed to define the role of echocardiography in PAVSD. Non-invasive evaluations...
Treatment Outcome of Penicillin-resistant S. Pneumoniae Infection
Min Sook Choi, Young Won Kim, Dong Soo Kim, Kyung Won Lee
Clin Exp Pediatr. 2001;44(2):149-153.   Published online February 15, 2001
Purpose : Streptococcus pneumoniae is a normal flora and common pathogen of the upper respiratory tract. S. pneumoniae infections are estimated to cause not only localized infection such as pneumonia, and otitis media, but also systemic infections, for example meningitis, sepsis, and so on. Recently, the resistance of S. pneumoniae to penicillin and multidrug has been rapidly increasing in many...
Relationship between Brain MRI and Neurodevelopmental Outcome in Term Infants with Severe Hypoxic Ischemic Encephalopathy
Sun Young Park, Kyoung Sim Kim, Sung Soo Rim, Byung Soon Kang, Eun Young Kim, Yong Wook Kim, Se Jong Kim
Clin Exp Pediatr. 2001;44(2):139-148.   Published online February 15, 2001
Purpose : We analyzed the relationship between MRI patterns and neurologic outcome and explored the effectiveness of MRI as a tool for predicting the outcome. Methods : We analyzed 23 full term infants with severe HIE retrospectively who were admitted to our NICU from Sep. 1993 to May 1998. Their MRI findings were classified into 4 patterns : type I :...
Long-term Clinical Follow-up of Korean Children with Wilson Disease; Twenty Years` Experience
Jin Soo Moon, Jae Sung Ko, Jeong Kee Seo
Clin Exp Pediatr. 2001;44(2):127-138.   Published online February 15, 2001
Purpose : To investigate the clinical features of long-term follow-up, and the treatment responses in Korean children with Wilson disease(WD). Methods : The clinical data from ninety-two children with WD, diagnosed at Seoul National University Hospital from 1976 to 1999, were reviewed. Mean duration of follow-up was 5¡¾4.5 years. We analysed the patient's records based on the clinical manifestations, laboratory findings,...
Prevalence and Epidemiologic Charicteristics of Chronic Recurrent Headache in Primary School Children
Young-Il Rho, Young-Bong Park, Eun Seok Yang, Sang Kee Park, Eun Youngn Kim, Jong Park, Kyung-Rye Moon
Clin Exp Pediatr. 2001;44(2):119-126.   Published online February 15, 2001
Purpose : The purpose of the study was to determine the prevalence of chronic recurrent headache and the factors associated with it among primary school children. Methods : The survey was performed by a special questionnaire on one thousand and eleven children in grades 4 to 6 at primary schools from 1 to 30 June 1999 in Gwangju city. Results : Prevalence...
A Case of Xp21 Contiguous Gene Deletion Syndrome with Hyperglycerolemia, Congenital Adrenal Hypoplasia and Duchenne Muscular Dystrophy
Dae-Won Shin, Jun Huh, Hong-Jin Lee, Won-Ill Park, Kyung-Ja Lee, Yoon-Sook Shin, D.R. Sjarif, B.T. Poll-The
Clin Exp Pediatr. 2001;44(1):83-88.   Published online January 15, 2001
On Xp21 region several genes such as adrenal hypoplasia congenita(AHC) gene, glycerol kinase (GK) gene and Duchenne muscular dystrophy(DMD) gene are located contiguously. If there is a long deletion in that region, various combination of genetic defect can be occurred from one kind of genetic defect to all three kinds of genetic defect simultaneously. In case of more than two...
Factors Affecting the Presence of Menarche and Final Adult Height in Adult Female Patients with Congenital Adrenal Hyperplasia of 21-Hydroxylase Deficiency
Seong Yong Lee, Chae Kyoung Song, Min Ho Jung, Jin Soon Hwang, Sei Won Yang
Clin Exp Pediatr. 2001;44(1):75-82.   Published online January 15, 2001
Purpose : Amenorrhea and short stature are serious complications in patients with congenital adrenal hyperplasia of 21-hydroxylase deficiency(CAH). We analysed several factors influencing the presence of menarche and final adult height in these patients. Methods : We retrospectively reviewed medical records of 24 female patients with CAH. We analysed possible factors affecting the menarche and final adult height, such as clinical...
Tumor Vaccine Effect by IL-16 Gene Transfer into Murine Neuroblastoma Model
Hyun-Sang Cho, Chong Young Park
Clin Exp Pediatr. 2001;44(1):68-74.   Published online January 15, 2001
Purpose : Interleukin(IL)-16 is a potent chemoattractant factor for CD4＋ T cells, monocytes, and eosinophils. It up-regulates IL-2R on CD4＋ T lymphocytes and regulates the function of antigen presenting cells. We used retrovirus-mediated gene transfer of the human IL-16 gene into the neuro-2a cells, which is the murine neuroblastoma cell lines, to investigate whether locally secreted IL-16 might generate anti-tumor...
Clinical Study of Effectiveness Topiramate in Children with Intractable Epilepsy
Young Mi Choi, Sa Jun Chung
Clin Exp Pediatr. 2001;44(1):62-67.   Published online January 15, 2001
Purpose : Topiramate(TPM) is a new anticonvulsant with multiple action mechanisms which should theoretically represent a wide therapeutic spectrum. However, there is still little clinical experience of its use in Asian children with epilepsy. Methods : The patients were total 96 children who were treated with more than 2 anticonvulsants but poorly controlled seizure activity. TPM was given as add-on therapy...
Risk Factors of Renal Scar After Acute Pyelonephritis in Children
Chur Woo You
Clin Exp Pediatr. 2001;44(1):54-61.   Published online January 15, 2001
Purpose : In this study we re-evaluated the known risk factors of pyelonephritic scarring in children. Methods : A prospective study was performed on 36 acute pyelonephritis(APN) patients who were diagnosed as first acute pyelonephritis on 99mTc-DMSA scan between September 1998 and March 2000 in Masan Samsung Hospital. According to the prescence of remnant lesions on the 99mTc-DMSA scan performed...
Influence of Epstein-Barr Virus Infection on Outcome of Coronary Artery Lesions in Patients with Kawasaki Disease
Hye-Yung Ahn, Hyang-Sook Kim, Jo-Won Jung, Ki-Soo Pai
Clin Exp Pediatr. 2001;44(1):46-53.   Published online January 15, 2001
Purpose : Kawasaki disease(KD) may be linked to primary infection by certain common viruses. KD concurrent with Epstein-Barr virus(EBV) suggests the possibility of an etiologic agent related to the KD rather than to the EBV infection itself, but, the influence on coronary complication is unclear. To establish whether infection with EBV contributed to the outcome of coronary artery lesions in...
Assessment of Endogenous Nitric Oxide Formation in the Neonate : Measurement of Urinary Nitrite and Citrulline Concentrations
Young Ho Kim, Ki Hwan Yu, Young Sook Hong, Sun Kyum Kim
Clin Exp Pediatr. 2001;44(1):40-45.   Published online January 15, 2001
Purpose : At birth, as the fetus adjusts to the “new world”, the fetal pulmonary circulation undergoes a striking transition, characterized by an immediate rise in pulmonary blood flow and a sustained decrease in pulmonary vascular resistance(PVR). In the factors which reduce PVR after birth, are ventilation of the lung by gas, increase of oxygen tension in pulmonary vascular system,...
A Comparative Study of the Effects of Intravenous Indomethacin and Oral Mefenamic Acid in the Treatment of Premature Infants with Patent Ductus Arteriosus
Hae Jung Park, Yoon Suk Jung, Nam Soo Kim, Chang Ryul Kim, Hyuk Kim, Soo Jee Moon
Clin Exp Pediatr. 2001;44(1):32-39.   Published online January 15, 2001
Purpose : For the management of patent ductus arteriosus(PDA) in premature infants, fluid restriction, correction of anemia, mechanical ventilation, diuretics, and surgery have been used, and the closure rate of PDA has improved significantly since the introduction of indomethacin and mefenamic acid as pharmacologic treatments of PDA. We studied to evaluate and compare the therapeutic effects of indomethacin and mefenamic...
The Correlation Between the TSH Level in Neonatal Screening Test and the Prognosis of Congenital Hypothyroidism
Hong Sun Park, Kye Shik Shim, Kyuchul Choeh
Clin Exp Pediatr. 2001;44(1):25-31.   Published online January 15, 2001
Purpose : It is important to diagnose and treat newborn patients with congenital hypothyroidism as soon as possible because of neurodevelopmental outcome. If we can detect more severe forms of congenital hypothyroidism with neonatal screening test, the results of treatment will improve. Methods : Sixty-four term infants whose TSH levels in neonatal screening test had been higher than 20μIU were recalled....
TOPICS

Browse all articles >

ARTICLE CATEGORY

Browse all articles >

BROWSE ARTICLES
FOR CONTRIBUTORS
ABOUT
Editorial Office
Korean Pediatric Society
#1606 Seocho World Officetel, 19 Seoun-ro, Seocho-ku, Seoul 06732, Korea
Tel: +82-2-3473-7306    Fax: +82-2-3473-7307    E-mail: office@e-cep.org                

Clinical and Experimental Pediatrics is an open access journal. All articles are distributed under the terms of the Creative Commons Attribution NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/)

Copyright © 2026 by Korean Pediatric Society.      Developed in M2PI