To determine the clinical manifestations and outcomes of patients with tracheoesophageal fistula (TEF) and esophageal atresia (EA) born at a single neonatal intensive care unit. A retrospective analysis was conducted for 97 patients with confirmed TEF and EA who were admitted to the neonatal intensive care unit between 1990 and 2007. The rate of prenatal diagnosis was 12%. The average gestational age... |
Purpose : Transient tachypnea of the newborn (TTN) is usually benign and improves within 72 hours. However, it can also progress to prolonged tachypnea over 72 hours, profound hypoxemia, respiratory failure, and even death. The aim of this study is to find predictable risk factors and describe the clinical courses and outcomes of prolonged TTN (PTTN). Methods : The medical records... |
Purpose : Childhood accidents have been increasing recently. Accidents rank as the leading cause of childhood mortality and morbidity. We performed this study to evaluate the causes of childhood accidents. Methods : The authors analysed retrospectively the medical records of 6,410 cases of childhood accidental injuries who visited the emergency room of Asan Medical Center from January 1990 to December... |
This is the first reported case of a unique interstitial deletion involving the long arm of chromosome 17 in a Korean male infant born to parents with normal karyotype. The patient presented with multiple congenital malformations suggestive of chromosomal anomaly including round face, upslanted palpebral fissure, hypertelorism, posteriorly rotated low set ear, micrognathia, microcephaly, finger- like thumb, bilateral hearing loss,... |
Purpose : This study was done to evaluate the clinical and pathologic aspects of allergic colitis. Methods : This study evaluated 19 infants who presented with fresh blood mixed stools. Limited colonoscopy and biopsy were performed. Among the 19 infants, 13 infants were diagnosed as allergic colitis by histological findings. We analyzed the clinical and histological characteristics of 13 infants. Results : Male and female... |
Methylmalonic acidemia is a metabolic disorder of amino acid and fatty acid metabolism. A Female infant, who was diagnosed as methylmalonic acidemia based on findings; methylmalonic aciduria, metabolic acidosis with increased anion gap, hyperammonemia, has been followed up for 9 months. She has been placed on the planned diet according to Ross metabolic formula nutrition support protocol. The diet is... |
Purpose : To determine whether the prophylactic treatment with recombinant human erythropoietin(rHuEPO) for the anemia of prematurity would reduce the need for blood transfusions. Methods : We randomly assigned 17 premature infants to therHuEPO group and the control group. For the rHuEPO group (n=9, birth weight=1210¡¾156 g, gestational age=31.7¡¾1.9wk), rHuEPO (400U/kg) was given three times a week for 4 weeks, plus iron (8 mg/kg/day) and vitamin... |
Purpose : We tried to know normal range of auditory brainstem responses in premature and fullterm infants who have no rksk factor during perinatal period and to determine that the abnormal ABR in premature and fullterm infants may predict developmental delay. Methods : ABR evaluations were performed on 283 premature and fullterm infants from NICU of the Asan Medical Center during... |
To know the causative agent of asptic meningitis, we performed blood and cerebrospinal fluid study on 24 children who had been admitted to the department of Pediatrics, Asan Medical Reference Laboratory, Japan. The most of the patients were young infants, and 15 cases of them were under 3 months of age. The male to female ratio was 1:1.4. We observed the main symptoms... |
We clinically reviewed four patients who were suffering from aseptic meningitis combined with polio-like paralysis and performed radiological, neurological and virological studies on them. Three patients were admitted to the department of Pediatrics. Asan Medical Center from March to August 1990, and one patient was admitted to the department of Pediatrics, Kangnam General Hospital. The results were as follows: 1) During the period... |
Influenza virus culture was performed in 149 patients with influenza-like illness who were admitted or visited to the Department of Pediatrics, Asan Medical Center from january 1991 to March,1991. The results were as follows : 1) Of the total 149 patients, influenza virus were isolated in the 15 cases. : 15 isolates were characterized by the WHO Collaborating Center for influenza : 7... |
We had treated a hepatic rickets in 6 infants with neonatal hepatitis from June 1989 to August 1990 at Asan Medical Center. The results were as follows 1) Age of 6 patients were below 4 months and 4 patients were male, 2 patients were female. 2) The clinical findings were hepatosplenomegaly(5 cases), jaundice(4 cases), craniotabes (4 cases), failure to thrive(2 cases), hypocalcemiac seizure(2... |
Kawasaki disease is an acute febrile illness of unknown origin and most frequently affects infants and children under 5 years of age. Coronary aneurysms are the most serious complications and 15-20% of patient develop coronary aneurysm. We studied 50 children who wre diagnosed as Kawasaki disease and treated simultaneously with single high-dose gammaglobulin (2 gm/kg/day) and aspirin at Asan Medical Canter... |
We performed clinical and virological studies on 200 children with aseptic meningitis who had been admitted to the department of Pediatrics, Asan Medical Center from June, 1989 to August, 1990. The results were as follows; 1) There were total of 236 meningitis cases during this period, 13(5.5%) with bacterial meningitis, 3(1%) with tuberculous meningitis, 220(93.2%) with aseptic meningitis. Am이lg aseptic meningitis, 20(8.5%) were mumps meningitis. 2) Aseptic meningitis... |
Balloon atrial septostomy is accepted as the best initial palliative treatment in infants with certain types of cyanotic congenital heart disease and the importance of prompt creation of atrial communi- cation can not be overemphasized in these patients. Balloon atrial septostomy is performed through femoral vein using percutaneous technique in most cases and is rarely done by cut down approach. However, percutaneous femoral vein... |
Clinical, echocardiographic and angiographic findings of a very rare case of cardiac malformation is presented. The main features were tricuspid atresia, coronary sinus septal defect, and double orifice mitral valve. These defects were correctly diagnosed by echocardiography and were confirmed by angiocardiography. This patient was palliated successfully with blade balloon atrial septostomy and bidirectional cavopulmonary shunt. To the best of our knowledge, this is the... |
In order to find out the incidences of muscular ventricular septal defect and multiple ventricular septal defects in cases with isolated ventricular septal defect, tetralogy of Fallot, complete endocar- dial cushion defect, complete transposition of the great arteries, corrected transposition of the great arteries and double outlet right ventricle, a retrospective analysis of 620 left ventriculograms were performed. The surgical and echocardiographic findings were... |
To determine the incidence of cardiac arrhythmias of the school children, we have performed heart screening by the questionare and EKG and physical examination from September 1984 to October 1987 in Seoul. 1) The incidence of the cardiac arrhythmias was 1.27%. 2) There were 449 cases of heart diseases detected. Among these heart diseases there were congeni- tal heart diseases in 82 cases (0.31%), acquired heart diseases... |
Ventricular tachycardia (VT) is uncommon, but is in increasing tendency probably due to better case detection and longer survival of the patients with complex congenital heart disease. Widespread use of 24 hour ECG has contributed a lot to better understanding of ventricular tachycardia. Fourteen cases of ventricular tachycardia diagnosed by 24 hour ECG at Seoul National Children’ s Hospital from Feb. 1986 to Sep.... |
Sixteen cases of critical arrhythmia in children were prospectively studied at the department of pediatrics, Seoul National University Hospital, from Oct. 1986 to Apr. 1988 in order to determine the efficacy and side effect of amiodarone treatment in children. Their ages ranged from 5 months to 17 years with 2 patients younger than 1 year of age. The most frequent indication of amiodarone treatment... |
Idiopathic pulmonary hemosiderosis is an uncommon disease of undetermined cause that is char- acterized by periodic episodes of cough, hemoptysis, widespread pulmonary infiltrates and hypo- chromic anemia. Two cases of idiopathic pulmonary hemosiderosis were diagnosed after open lung biopsy. It revealed hemosiderin and hemosiderin-laden macrophage. There were no specific causes for pulmo- nary hemorrhage. We report 2 cases of idiopathic pulmonary hemosiderosis with brief review... |