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Letter to the Editor
Accuracy of predicted adult height using the Greulich-Pyle method and artificial intelligence medical device
Dongho Cho, Yun Sun Choi, Hayun Oh, Young min Ahn, Ji-Young Seo
Clin Exp Pediatr. 2023;66(3):145-147.   Published online January 25, 2023
Original Article
Survey of Korean pediatrician’s perceptions of barriers to and improvements in breastfeeding
Seong Phil Bae, Woo Ryoung Lee, Won-Ho Hahn, Hye-Jung Shin, Young Min Ahn, Son Moon Shin, Yong Joo Kim, Ellen Ai-Rhan Kim, Youn Jeong Shin, Dae Yong Yi, Soon Min Lee, Juyoung Lee, Jin A Lee, Sung-Hoon Chung, Euiseok Jung, Eui Kyung Choi, Ju Sun Heo
Clin Exp Pediatr. 2022;65(11):540-546.   Published online July 29, 2022
Question: What barriers to breastfeeding do Korean pediatricians perceive?
Finding: Regardless of medical institution, breastfeeding counseling for parents is currently limited, and breastfeeding is commonly discontinued due to various maternal and neonatal factors.
Meaning: To promote breastfeeding, increasing pediatrician participation in breastfeeding counseling with the establishment of appropriate breastfeeding counseling fees and the expansion of practical and high-quality breastfeeding education for medical staff should be considered.
Review Article
Neonatology (Perinatology)
Breastfeeding and vitamin D
Ju Sun Heo, Young Min Ahn, Ai-Rhan Ellen Kim, Son Moon Shin; for the Korean Society of Breastfeeding Medicine
Clin Exp Pediatr. 2022;65(9):418-429.   Published online December 14, 2021
∙ Exclusively breastfed infants are at risk of developing vitamin D deficiency associated with hypocalcemia, rickets, and various health outcomes.
∙ The prevalence of vitamin D deficiency in breastfed infants differs vastly between studies and nations at 0.6%–91.1%.
∙ The vitamin D content of breast milk does not meet the requirements of exclusively breastfed infants.
∙ Most international guidelines recommend that breastfed infants be supplemented with 400 IU/day of vitamin D during the first year of life.
∙ Vitamin D intake (milk+supplements) of 800 IU/day can be considered in preterm infants along with biochemical monitoring.
Hereditary angioedema in childhood
Young Min Ahn
Clin Exp Pediatr. 2020;63(1):18-19.   Published online January 15, 2020
Original Article
Positive association of breastfeeding on respiratory syncytial virus infection in hospitalized infants: a multicenter retrospective study
Min Jeong Jang, Yong Joo Kim, Shinhye Hong, Jaeyoon Na, Jong Hee Hwang, Son Moon Shin, Young Min Ahn
Clin Exp Pediatr. 2020;63(4):135-140.   Published online November 12, 2019
Question: Human milk has stronger antiviral, antibacterial, and anti-inflammatory properties compared with formula milk. How dose breastfeeding affect respiratory syncytial virus infection in Korea?
Finding: Breastfed infants required less oxygen therapy and possible intensive care unit admission than artificial formulafed infants during respiratory syncytial virus infection.
Meaning: This protective role of breast milk on RSV severity can be a supporting evidence for promoting breastfeeding in Korea.
General Pediatrics
Sudden unexpected cardio-respiratory arrest after venipuncture in children
Goun Jeong, Son Moon Shin, Nam Su Kim, Young Min Ahn
Clin Exp Pediatr. 2018;61(4):108-113.   Published online April 23, 2018

This study aimed to investigate the clinical and socioenvironmental characteristics of sudden cardiorespiratory arrest after venipuncture in children.


We conducted a retrospective email-based survey of all members of the Korean Pediatric Society. The questionnaire included items on patient demographics, socioenvironmental circumstances of the venipuncture, type of cardiorespiratory arrest, symptoms and signs, treatment, prognosis, and presumed cause of the arrest.


Fourteen patients were...

Sleep problems in children and adolescents at pediatric clinics
Dong Soon Kim, Cho Long Lee, Young Min Ahn
Clin Exp Pediatr. 2017;60(5):158-165.   Published online May 31, 2017

To investigate the frequency of childhood sleep problems at pediatric clinics in Seoul and Gyeonggi provinces.


Children (n=936) and their parents who visited 5 primary and 1 secondary pediatric outpatient clinics were invited to complete a Pediatric Sleep Questionnaire.


Among patients, 901 (96.3%) answered questionnaires in sufficient detail for evaluation. The participant's mean age was 4.35±3.02 years (range, 0–18 years). The male...

Clinical characteristics and prevalence of vitamin D insufficiency in children less than two years of age
Ji Hyun Yoon, Cheong Soo Park, Ji Young Seo, Yun Sun Choi, Young Min Ahn
Clin Exp Pediatr. 2011;54(7):298-303.   Published online July 31, 2011

To evaluate the clinical characteristics of vitamin D deficiency and its association with iron deficiency anemia (IDA).


A total of 171 children aged less than two years underwent 25-hydroxyvitamin D3 tests between January 2007 and July 2009. The study was classified into two groups: normal and vitamin D insufficiency, by their vitamin 25-hydroxyvitamin D3 levels.


In total, 120 children were in the...

Review Article
Treatment of obstructive sleep apnea in children
Young Min Ahn
Clin Exp Pediatr. 2010;53(10):872-879.   Published online October 31, 2010

Obstructive sleep apnea (OSA) in children is a frequent disease for which optimal diagnostic methods are still being defined. Treatment of OSA in children should include providing space, improving craniofacial growth, resolving all symptoms, and preventing the development of the disease in the adult years. Adenotonsillectomy (T&A) has been the treatment of choice and thought to solve young patient's OSA...

Original Article
Drug resistance of Mycobacterium tuberculosis in children
Soo Jin Lee, Young Min Ahn, Hee Jin Kim
Clin Exp Pediatr. 2009;52(1):61-67.   Published online January 15, 2009
Purpose : The rate of drug-resistant tuberculosis (DR-TB) in children is an indicator of the effectiveness of TB control programs in the community. This study aimed to assess the prevalence of DR-TB in children and evaluate TB management. Methods : Between January 1999 and July 2007, drug susceptibility tests for anti-TB drugs were employed for patients aged less than 19...
Case Report
A case of restless legs syndrome in a child presenting with growing pains
Dong Soon Kim, Hong Beom Shin, Young Min Ahn
Clin Exp Pediatr. 2008;51(11):1222-1227.   Published online November 15, 2008
Restless legs syndrome (RLS) is a common neurological sleep disorder in adults characterized by the following diagnostic criteria: an urge to move that is usually associated with unpleasant sensations and symptoms that are worse at rest, relieved by movement, and most severe at night. The definite diagnosis of RLS in children is stricter and consists of self-description of leg discomfort...
Cytogenetic evaluation of a patient with ring chromosome 9 presenting failure to thrive and developmental delay
Yun Mi Park, Han Nae Nho, Sook Za Kim, Young Min Ahn
Clin Exp Pediatr. 2008;51(4):426-430.   Published online April 15, 2008
We report clinical, cytogenetic, and fluorescence in situ hybridization (FISH) studies of a patient with ring chromosome 9. She presented with failure to thrive, facial dysmorphysm and mild psychomotor development delay in the absence of major malformations. Peripheral blood karyotype of the patient was 46,XX,r(9)(p24q34). G-band analysis suggested no loss of material in the ring chromosomes. FISH analysis using the...
Original Article
Isolation rate of 4 type virus of acute gastroenteritis in full-term neonates during neonatal period
Soo Kyoung Moon, Jae In Lee, Hye Sun Yoon, Young Min Ahn
Clin Exp Pediatr. 2007;50(9):855-861.   Published online September 15, 2007
Purpose : The most common causes of acute viral gastroenteritis in newborn period are rotavirus, astrovirus, norovirus and enteric adenovirus. This study was designed to investigate the clinical characteristics, clinical symptoms, isolation rate and distribution of these viruses in full-term neonates during neonatal period. We also studied the influence on the viral isolation rate by postnatal care place and feeding...
Health status of children in low socioeconomic conditions
Hee Kyoung Choi, Jeong A Her, Seong Hee Jang, Dal Hyun Kim, Kyoung Lim Yoon, Young Min Ahn
Clin Exp Pediatr. 2006;49(1):24-28.   Published online January 15, 2006
Purpose : The purpose of this study was to investigate the health status and nutritional condition of children living in a low-income community through anthropometric, laboratory evaluation. Methods : A community-based survey identified children below 15 years living in a low-income community. Their weight, height, visual acuity, hearing level and dental status were measured. Blood sample were obtained on June and...
Clinical Usefulness of Rapid Antigen Test on the Diagnosis of Influenza
Jae Seon Kim, Hyon Joo Choi, Young Min Ahn, Young Ok Hwang
Clin Exp Pediatr. 2005;48(12):1348-1353.   Published online December 15, 2005
Purpose : Influenza is a respiratory disease which prevails widely every year and shows high morbidity and mortality among not only chronic invalids and the old, but also among infants and young children. To prevent community-acquired influenza infection, to facilitate prompt antiviral therapy and to avoid unnecessary use of antibiotics, an easy, rapid diagnostic method for the influenza virus is...
A Clinical Study of Chronic Functional Constipation in Children Treated for more than Five Months
Young Min Kim, Sung Yun Choi, Sun Hwan Bae, Young Min Ahn
Clin Exp Pediatr. 2004;47(11):1186-1192.   Published online November 15, 2004
Purpose : The purpose of this study was to evaluate the clinical features and the courses and effects of long-term treatment, and to analyze the association between clinical features and duration of therapy in chronic functional constipation in children. Methods : This study enrolled 57 children with chronic functional constipation who were treated in the Eulji Hospital for more than...
Case Report
A Case of Vocal Cord Dysfunction
Jeoung A Her, Hee Kyoung Choi, Chang Hee Son, Young Min Ahn
Clin Exp Pediatr. 2004;47(5):574-578.   Published online May 15, 2004
Vocal cord dysfunction is a recently described entity in which paradoxical adduction of the vocal cords produces airflow obstruction at the level of the larynx. Recurrent wheezing results, which may imitate asthma. Inspiratory closure of the cords can also cause stridor, commonly misdiagnosed as an upper airway obstruction of undefined cause. The acute presentation is often dramatic and has led...
A Case of Glutaric Aciduria Type I with Macrocephaly
Woo Jong Shin, Yeo Ok Moon, Hye Ran Yoon, Eun Sil Dong, Young Min Ahn
Clin Exp Pediatr. 2003;46(3):295-301.   Published online March 15, 2003
Glutaric aciduria type 1(GA1) is an autosomal recessive disorder of the lysine, hydroxylysine and tryptophan metabolism caused by the deficiency of mitochondrial glutaryl-CoA dehydrogenase. This disease is characterized by macrocephaly at birth or shortly after birth and various neurologic symptoms. Between the first weeks and the 4-5th year of life, intercurrent illness such as viral infections, gastroenteritis, or even routine...
Original Article
Sudden Unexpected Death in Infancy (Analysis of 34 Cases Including 13 Autopsies)
Yeo Ok Moon, Hee Kyoung Choi, Jeoung-A Her, Woo Jong Shin, Myoung-A Kim, Seong Yong Lee, Seong Hee Jang, Eun Sil Dong, Chong Jae Kim, Young Min Ahn, Je Geun Chi
Clin Exp Pediatr. 2002;45(9):1065-1074.   Published online September 15, 2002
Purpose : The purpose of this study is to analyze the epidemiologic characteristics of sudden unexpected death in infancy and to evaluate the importance of postmortem autopsy. Methods : We reviewed, retrospectively, medical records of 34 infants admitted to Kangnam General Hospital from January 1987 to December 2001 because of sudden unexpected death. We investigated the cause of death through medical...
Case Report
A Case of Marshall-Smith Syndrome
Yeo Ok Moon, Woo Jong Shin, Youn Jeong Shin, Eun Sil Dong, Young Min Ahn
Clin Exp Pediatr. 2002;45(7):906-911.   Published online July 15, 2002
Marshall-Smith syndrome is characterized by a triad of facial dysmorphism, failure to thrive and accelerated osseous maturation. We report a one-month-old male infant with of this rare syndrome, with laryngeal anomalies who died at 6 months of age with pneumonia. This is the first case of Marshall-Smith syndrome in Korea.
Original Article
Local Rifampicin Instillation Therapy for Suppurative Bacillus Calmette-Gu rin Lymphadenitis
Mee Jeong Kim, Seong Hee Jang, Young Min Ahn, Mi Kyoung Kang, Sang Jae Kim
Clin Exp Pediatr. 2002;45(4):454-458.   Published online April 15, 2002
Purpose : Bacillus Calmette-Gu rin(BCG) lymphadenitis is one of the most common complications of BCG vaccination. The involved lymph nodes usually subside spontaneously, but they may become enlarged and form an abscess. Treatment of these infants is controversial. The Pan American Health Organization recommends local isoniazid or rifampicin instillation for patients with suppurative BCG lymphadenitis. Methods : The study group comprised...
Clinical Manifestations of Group A β-Hemolytic Streptococcal Pharyngits and Usefulness of Rapid Antigen Test
Youn Jeong Shin, Seong Hee Jang, Eun Sil Dong, Young Min Ahn, Myung Suk Ku
Clin Exp Pediatr. 2001;44(7):732-741.   Published online July 15, 2001
Purpose : Accurate diagnosis of group A streptococcal(GAS) pharyngitis and appropriate antimicrobial therapy are important, particularly to prevent nonsuppurative sequelae and to reduce the improper use of antibiotics. Because the clinical presentation of pharyngitis does not reliably predict the etiologic agent, when GAS infection is suspected, diagnosis should be based on the result of a throat swab culture or antigen-detection...
Case Report
A Case of Wolf-Hirschhorn Syndrome with Long Term Survival Diagnosed by Fluorescent In-situ Hybridization(FISH)
Eun Sil Dong, Mee Jeong Kim, Young Min Ahn, Myoung Sook Koo, Hwan Keuk Yong, Anna Lee
Clin Exp Pediatr. 2000;43(3):438-443.   Published online March 15, 2000
Wolf-Hirschhorn syndrome is a multiple malformation syndrome associated with mental and developmental retardation, resulting from a deletion at the short arm of chromosome 4(4p16.3). We report a 11-year-old girl with Wolf-Hirschhorn syndrome, who was presented with severe growth and mental retardation along with characteristic features-frontal bossing, hypertelorism, downslanting of the palpebral fissures and fishlike lips. The diagnosis was confirmed by...
Original Article
Drug-Resistant Tuberculosis in Children
Seong Hee Jang, Yoon Hwa Cha, Young Min Ahn, Sang Jae Kim
Clin Exp Pediatr. 1997;40(6):818-825.   Published online June 15, 1997
Purpose : Initial drug resistance of children with tuberculosis is a useful performance indicator of tuberculosis control programme in the concerned country because it represented infection transmitted from adult patients with either primary or acquired drug resistance. But there have been a few studies available. The present study was made to know the incidence of drug-resistant tuberculosis in hopes of...
Case Report
A Case of Respiratory Syncytial Virus Infection Presented with Apnea
Eun Ha Choi, Seong Hee Jang, Young Min Ahn
Clin Exp Pediatr. 1996;39(4):558-561.   Published online April 15, 1996
Respiratory syncytial virus(RSV) is currently implicated as the most common and otentially serious viral respiratory pathogen of young infants. Apnea in association with RSV infection occurred in about 18% of the infants. Premature birth and a young postnatal age were risk factors for development of apnea with RSV disease. We experienced a case of RSV infection in a 37 day-old...
Original Article
Epidemiology and Vaccine Efficacy of Measles During the 1993 measles Epidemic
Soon Ki Kim, Jong Woon Choi, Byong Kwan Son, Seung Nam Park, Churl Young Chung, Young Min Ahn, Chong Young Park, Ki Yang Ryoo, Woo Kap Chung, Hoan Jong Lee
Clin Exp Pediatr. 1995;38(6):778-785.   Published online June 15, 1995
Purpose : Because of increased measles incidence in Korea during 1993 and the recent finding of genomic differences between vaccine virus and contemporary wild measles viruses, we conducted a measles vaccine efficacy study involving children ages 1 to 5 yeark, with the demographic analysis of patients brought to the hospitals during measles outbreak that had occurred 1993 in Seoul and...
A Clinical Study on Urinary Tract Infection in Infants and Children
Yoon Hwa Cha, Hee Ran Choi, Seong Hee Jang, Young Min Ahn
Clin Exp Pediatr. 1994;37(11):1488-1499.   Published online November 15, 1994
This is a report of clinical study on the 63 patients of symptomatic urinary tract infection who were hospitalized at the Department of Pediatrics in Kangnam General Hospital during the period between the May of 1989 and the September of 1992. The observation results were as follows: 1) The frequency of urinary tract infection (UTI) was the highest in children...
Case Report
A Case of Prader-Willi Syndrome with Diabetes Mellitus
Hee Ran Choi, Eun Ha Choi, Seong Hee Jang, Young Min Ahn
Clin Exp Pediatr. 1994;37(4):565-572.   Published online April 15, 1994
Prader-Willi syndrome is characterized by infantile hypotonia, mental retardation, hyperhagia, hypogonadism and obestiy. Approximately 60% of all PLW syndrome show an interstitial deletion of chromosome 15, 37% have apparently normal chromosome, and 3.6% have a variety of other abnormalities involving chromosome 15. Diabetes mellitus has been considered a component of PLW syndrome and the incidence is about 7%. We...
A Case of Cyclic Neutropenia
Yoon Hwa Cha, Hye Sun Lee, Young Min Ahn, Myoung Sook Koo
Clin Exp Pediatr. 1993;36(7):1009-1015.   Published online July 15, 1993
Cyclic Neutropenia is a benign, unusual hematologic disorder characterized by regularly recurring episodes of severe neutropenia occurring approximately every 21 days. Beside neutrophils, monocytes, lymphocytes, platelets and reticulocytes all cycle with strict periodicity suggest that this disease should be viewed as cyclic hematopoiesis, not merely as cyclic neutropenia. During neutropenic periods, patients regularly experience aphthous stomatitis, fever, malaise, cervical lymphadenitis, cutaneous...
Original Article
A Clinical Study on Aseptic Meningitis Combined with Polio-Like Paralysis
Woong Young Moon, Ki Soo Kim, Young Seo Park, Hyung Nam Moon, Chang Yee Hong, Dae Chul Suh, Si Joon Yu, In Young Seong, Young Min Ahn
Clin Exp Pediatr. 1993;36(4):485-494.   Published online April 15, 1993
We clinically reviewed four patients who were suffering from aseptic meningitis combined with polio-like paralysis and performed radiological, neurological and virological studies on them. Three patients were admitted to the department of Pediatrics. Asan Medical Center from March to August 1990, and one patient was admitted to the department of Pediatrics, Kangnam General Hospital. The results were as follows: 1) During the period...
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