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Case Report
Use of intravenous immunoglobulin in a disseminated varicella infection in an immunocompromised child
Jae Hong Kim, Dae Hyun Kwon, E Young Bae, Seung Beom Han, Jae Wook Lee, Nack Gyun Chung, Dae Chul Jeong, Bin Cho, Jin Han Kang, Hack Ki Kim
Clin Exp Pediatr. 2014;57(8):370-373.   Published online August 25, 2014

Varicella-zoster virus infection can lead to severe illness in immunocompromised patients. Further the mortality rate of disseminated varicella infection is extremely high particularly in immunocompromised children. We report a case of disseminated varicella infection in a child with acute lymphoblastic leukemia who was receiving chemotherapy, but was initially admitted with only for acute abdominal pain. The patient rapidly developed severe...

A Case of Recurrent Herpes Simplex Virus Disease of a Preterm Infant, Who Needed Continuous Oral Acyclovir Suppressive Therapy
Sung Seok Kim, Ki Woong Hong, Eun Ryoung Kim, Young-Don Kim, Kyoo Man Lee
Clin Exp Pediatr. 2003;46(9):939-949.   Published online September 15, 2003
Neonatal herpes simplex virus(HSV) infections result in significant morbidity and mortality. Although acyclovir treatment has improved survival, severe neurological sequelae can occur in the majority of survivors. HSV infections limited to the skin, eyes and mouth(SEM) can cause neurologic impairment. A direct correlation exists between the development of neurologic deficits and the frequency of cutaneous HSV recurrences. National Institutes of...
Original Article
A Clinical Study on Varicella zoster Virus Infection, Relating Factors and Treatment in Pediatric Cancer Patients
Yoon Sook Chung, Su Hyun Kim, Ki Joong Kim, Hahng Lee
Clin Exp Pediatr. 2001;44(11):1289-1294.   Published online November 15, 2001
Purpose : We performed this study to contribute to the prevention and treatment of Varicella zoster virus infection in pediatric cancer patients through understanding of VZV infection, acyclovir efficacy and varicella vaccination. Methods : A retrospective study was performed by reviewing chart from January 1988 to January 2001. Results : The diseases among 19 cases were leukemia. 12 cases were solid...
Case Report
A Case of Ramsay-Hunt Syndrome
Ok Ja Jeong, Se Wook Oh, Se Chang Ham, Yong Won Park
Clin Exp Pediatr. 2000;43(12):1608-1612.   Published online December 15, 2000
Ramsay Hunt Syndrome was initially described by Ramsay Hunt in 1907 as herpes zoster of the geniculate ganglion. The frequency of RHS in patients with herpes zoster has been calculated to be about 1%. RHS affects mostly adults; however a small number of children with herpes zoster oticus have been reported. We describe a case of RHS in a healthy...
A Case of Acyclovir Induced Acute Tubular Necrosis
Mi Ya Park, Mee Kyung Namgoong, Hwang Min Kim, Baek Keun Lim, Sun Hee Jung
Clin Exp Pediatr. 1995;38(9):1283-1287.   Published online September 15, 1995
Acyclovir is generally regarded as a safe and highly effective antiviral agent in normal, as well as in immunocompromised hosts. Major renal complication was unusual. However, reversible renal dysfunction has been reported. The impairment of renal nephropathy resulting from crystal formation in the renal tubules or the collecting ducts. But we experienced a case of immunocompetent patient who developed severe...
Original Article
The Effect of Prolonged Treatment in Children with Chronic Hepatitis B with Combination of Alpha-Interferon and Acyclovir
Jeong Ok Hah, Kyoung A Lee
Clin Exp Pediatr. 1993;36(12):1701-1706.   Published online December 15, 1993
This study was conducted to evaluate the effect of prolonged treatment in children with chronic hepatitis B will combination of alpha-interferon and acyclovir. The study population consisited of & patients with chronic hepatitis B who showed histological findings compatible with chronic active hepatitis (4 cases) or chronic persistent hepatitis (3 cases) on liver biopsy and had elevated AST and ALT with...
A clinical study on varicella zoster virus infection and treatment in children with malignant lymphoproliferative disease.
Hak Won Kim, Jae Won Oh, Sung Hee Oh, Ha Baik Lee, Hahng Lee
Clin Exp Pediatr. 1991;34(9):1246-1254.   Published online September 30, 1991
Vaircella Zoster Virus (VZV) infection is usually a benign disease in normal hosts, but it is known to result in high risk for visceral dissemination and mortality in immunocompromised hosts, as in the children with malignant diseases, especially with malignant lymphoproliferative diseases. Therefore, passive or active immunization and antiviral therapeutic modality have been tried to control visceral dissemination and thus to decrease mortality in...
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