Journal of the Korean Pediatric Society 1995;38(9):1283-1287.
Published online September 15, 1995.
A Case of Acyclovir Induced Acute Tubular Necrosis
Mi Ya Park2, Mee Kyung Namgoong2, Hwang Min Kim2, Baek Keun Lim2, Sun Hee Jung1
1Department of Pathology, Yonsei University, Wonju College of Medicine, Wonju, Korea
2Department of Pediatricsy, Yonsei University, Wonju College of Medicine, Wonju, Korea
Acyclovir 투여로 인한 급성 신세뇨관 괴사 1례
박미야2, 남궁미경2, 김황민2, 임백근2, 정순희1
1연세대학교 원주의과대학 해부병리학교실
2연세대학교 원주의과대학 소아과학교실
Acyclovir is generally regarded as a safe and highly effective antiviral agent in normal, as well as in immunocompromised hosts. Major renal complication was unusual. However, reversible renal dysfunction has been reported. The impairment of renal nephropathy resulting from crystal formation in the renal tubules or the collecting ducts. But we experienced a case of immunocompetent patient who developed severe and rapidly progressive acute renal failure due to tubular necrosis without crystal formation during the administration of acyclovir. So we report with a brief review and its related literatures.
Key Words: Acyclovir, Acute Tubular Necrosis, Crystal

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