| The etiologies and the clinical manifestations of hypoglycemia in infancy and childhood. |
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Nam Seon Beck, Dong Joo Shin, Heon Seok Han, Sei Won Yang, Hyung Ro Moon |
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Department of Pediatrics Seoul National University College of Medicine, Seoul, Korea |
| 영아 및 소아기 저혈당의 원인 및 임상상 |
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백남선, 신동주, 한헌석, 양세원, 문형로 |
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서울대학교 의과대학 소아과학교실 |
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Received: 29 September 1990 • Accepted: 30 November 1990 |
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| Abstract |
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To analysis age at onset, clinical manifestations, etiologies, complication and management of
hypoglycemia, the authors reviewed seventeen cases of hypoglycemia who were admitted to Seoul
National University Children’s Hospital because of hypoglycemic symtoms from March, 1982 to
February, 1990. In neonate group, which included five patients, their initial symtoms were apnea,
cyanosis, sweating and hand rigidity, with the causes of two hyperinsulinemic hypoglycemias, one Rh
incompatibility and one the product of DM mother, but one case had no causative factors. In infant
group, which included six patients who presented with seizures exclusively, the etiologies were five
hyperinsulinemic hypoglycemias and one primary adrenal insuficiency, and the other group (over one
year of age), which included six patients, presented with seizures except one case who presented with
drowsiness initially, the etiologies in this group were four ketotic hypoglycemias, one hyperin-
sulinemic hypoglycemia and one growth hormone deficiency. There were eight hyperinsulinemic
hypoglycemia cases in this review, all of them presented initially with seizure and six cases were
associated with mild to moderate developmental delay. Six cases out of eight underwent near-
total(95%) pacreatectomy with improvement of hypoglycemia but two cases showed persistent
seizure and developmental delay. The above results suggest the importance of early detection and
managment of hypoglycemia in infancy and childhood. |
| Key Words:
Hypoglycemia |
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