| Causative Organisms in Children with Bacterial Meningitis(1992-2002) |
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Hyun-Jung Kim, JI-Won Lee, Kyung-Yil Lee, Hyung-Shin Lee, Ja-Hyun Hong, Seung-Hoon Hahn, Kyung-Tai Whang |
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Department of Pediatrics, College of Medicine, The Catholic University of Korea, Seoul, Korea |
| 소아 세균성 수막염에서 원인균에 관한 고찰(1992-2002) |
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김현정, 이지원, 이경일, 이형신, 홍자현, 한승훈, 황경태 |
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가톨릭대학교 의과대학 소아과학교실 |
Correspondence:
Kyung-Yil Lee, Email: leekyungyil@catholic.ac.kr
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| Abstract |
Purpose
: This study was performed to assess the difference of organisms causing bacterial meningitis according to time.
Methods
: We analyzed retrospectively 40 medical records of bacteriologically proven meningitis from 1992 to 2002. We divided them into two groups; neonate's group(14 cases), and children's group(26 cases). The results of the neonate's group were compared with those of previously reported articles in Korea, in 1970s-1980s. The causative agents of the children's group were analyzed according to the stage before and after the introduction of H. influenza type b(Hib) vaccine.
Results
: In neonates, Group B streptococci(GBS) was the most common cause of bacterial meningitis. There was a trend in Korea that major causative agents of neonatal bacterial meningitis have changed from gram negative bacteria including E. coli to gram positive bacteria including GBS. In children, H. influenzae was isolated in six out of 11 cases(55%) in 1992-95, before the introduction of Hib vaccine, while two out of seven(29%) were isolated in 1999-2002, after the introduction of the Hib vaccine.
Conclusion
: Our study showed that the most common agent of neonatal bacterial meningitis was GBS. There was a trend that after the introduction of Hib vaccine, the incidence of H. influenza meningitis decreased in children. |
| Key Words:
Bacterial meningitis, H. influenzae type b vaccine, Neonate, Children |
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