| Analysis of Affecting Factors for Cortisol Level in Cord Blood |
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Hyun Jung Lim1, Chang Hun Song1, Eun Young Kim2, Sang Kee Park2 |
1Department of Obstetrics and Gynecology, College of Medicine, Chosun University, Gwangju, Korea
2Department of Pediatrics, College of Medicine, Chosun University, Gwangju, Korea |
| 제대혈 Cortisol 농도에 영향을 미치는 인자에 대한 연구 |
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임현정1, 송창훈1, 김은영2, 박상기2 |
1조선대학교 의과대학 산부인과학교실
2조선대학교 의과대학 소아과학교실 |
Correspondence:
Eun Young Kim, Email: sskey@chosun.ac.kr
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| Abstract |
Purpose
: Long-term stress to the fetus causes alterations in adrenal steroidogenesis. The purpose of this study was to analyze the association of cord blood cortisol with stress during delivery.
Methods
: Cord blood samples were collected from 58 neonates at once to labor. Cortisol was measured by RIA method(DPC, USA). Cortisol level according to gestational age(<34, 34-37, >38 wks) and method of delivery(Cesarean section vs. vaginal delivery), Apgar score and uterine contraction, were compared to know stress during labor.
Results
: Cortisol of cord blood had considerable differences between each group, according to gestational age(P<0.001). It was statistically higher in the cases of vaginal delivery than cessarian delivery(P<0.001). The concentration of cortisol was significantly higher according to duration of labor (P<0.05). There was a significant relationship between cortisol level and uterine contraction(P<0.05). The concentration of cortisol was significantly low when Apgar score at 1 min was low(P<0.05).
Conclusion
: Cord cortisol has close association with stress during labor. And so do with post birth prognosis of neonate. |
| Key Words:
Cord cortisol, Stress during labor |
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