Journal of the Korean Pediatric Society 1999;42(1):128-132.
Published online January 15, 1999.
A Case of Acute Myeloblastic Leukemia Transformed from Transient Myeloproliferative Disorder with Down Syndrome
Jae Eun Lee1, Seung Woo Baeck1, Wan Seob Kim1, Chun Hee Lee2
1Department of Pediatrics, Presbyterian Medical Center, Chonju, Korea
2Department of Clinical Pathology, Presbyterian Medical Center, Chonju, Korea
일과성 골수증식장애를 가진 다운 증후군 환아에서 발생한 급성 골수성 백혈병 1례
이재은1, 백승우1, 김완섭1, 이춘희2
1전주예수병원 소아과
2전주예수병원 임상병리과
Individuals with Down syndrome have a high incidence of hematologic diseases such as transient myeloproliferative disorder(TMD) & acute leukemia. Because it is difficult to distinguish TMD from acute myeloblastic leukemia, the diagnosis in neonate, who have Down syndrome, should be made with extreme caution. TMD usually undergoes spontaneous remission within a few months, but acute leukemia can develope after remission of TMD. We now report a case of acute myeloblastic leukemia that was a transformed TMD with Down syndrome.
Key Words: Transient myeloproliferative disorder, Down syndrome, Acute myeloblastic leukemia

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