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Review Article
Update on benign convulsions with mild gastroenteritis
Yeong Seok Lee, Ga Hee Lee, Young Se Kwon
Received July 21, 2021  Accepted December 15, 2021  
Benign convulsions with mild gastroenteritis (CwG) are characterized by afebrile convulsions associated with viral gastroenteritis in previously healthy infants and children. The main causative pathogens are rotavirus and norovirus. CwG occurs frequently in both East Asian and Western countries. The prevalence of CwG was reportedly not decreased by the introduction of rotavirus vaccines, and the prevalence of norovirus-associated CwG has...
Original Article
Endocrinology
The effect of low-dose intravenous bisphosphonate treatment on osteoporosis in children with quadriplegic cerebral palsy
Soon Jeong Moon, Young Min An, Soon Ki Kim, Young Se Kwon, Ji Eun Lee
Clin Exp Pediatr. 2017;60(12):403-407.   Published online December 22, 2017
Purpose

Quadriplegic children with cerebral palsy are more susceptible to osteoporosis because of various risk factors that interfere with bone metabolism. Pamidronate is effective for pediatric osteoporosis, but there are no guidelines for optimal dosage or duration of treatment in quadriplegic children with osteoporosis. We aimed to evaluate the efficacy of low-dose pamidronate treatment in these patients.

Methods

Ten quadriplegic patients on antiepileptic...

Case Report
Neurology
Complete occlusion of the right middle cerebral artery associated with Mycoplasma pneumoniae pneumonia
Ben Kang, Dong Hyun Kim, Young Jin Hong, Byong Kwan Son, Myung Kwan Lim, Yon Ho Choe, Young Se Kwon
Clin Exp Pediatr. 2016;59(3):149-152.   Published online March 31, 2016

We report a case of a 5-year-old girl who developed left hemiparesis and left facial palsy, 6 days after the initiation of fever and respiratory symptoms due to pneumonia. Chest radiography, conducted upon admission, showed pneumonic infiltration and pleural effusion in the left lung field. Brain magnetic resonance imaging showed acute ischemic infarction in the right middle cerebral artery territory....

Development of multifocal nodular lesions of a liver mimicking hepatic metastasis, following resection of an insulinoma in a child
Sook Young Jung, Ben Kang, Yoon Mee Choi, Jun Mee Kim, Soon Ki Kim, Young Se Kwon, Ji Eun Lee
Clin Exp Pediatr. 2015;58(2):69-72.   Published online February 28, 2015

Insulinoma, which arises from insulin-producing pancreatic beta cells, is a rare tumor in children. Only 5%-10% of insulinomas are malignant and undergo metastasis. We report a case of an 11-year-old girl who experienced hypoglycemia-related seizures induced by an insulinoma; after resection of the primary tumor, she developed hepatic focal nodular hyperplasia (FNH). Laboratory test results indicated marked hypoglycemia with hyperinsulinemia....

Review Article
Benign convulsion with mild gastroenteritis
Ben Kang, Young Se Kwon
Clin Exp Pediatr. 2014;57(7):304-309.   Published online July 23, 2014

Benign convulsion with mild gastroenteritis (CwG) is a type of afebrile seizure that occurs in children. CwG is defined as a convulsion in a previously healthy child with no known central nervous system infection or encephalopathy, accompanying mild diarrhea without fever, electrolyte imbalance, or moderate to severe dehydration. Convulsions in CwG are characterized by multiple brief episodes of generalized or...

Original Article
Clinical features of children's brain tumors according to location
Seung Jeong Han, Yun Hee Kim, Young Se Kwon, Yong Hoon Jun, Soon Ki Kim, Byong Kwan Son
Clin Exp Pediatr. 2006;49(1):76-81.   Published online January 15, 2006
Purpose : This study evaluated the clinical characteristics of brain tumors in children according to their location, the parental delay and the doctor's delay between the onset of symptoms and the diagnosis of a pediatric brain tumor. In addition, this study compared the relationship between the pre-diagnostic symptomatic interval and the tumor location. Methods : A retrospective study was undertaken of...
Clinical Characteristics of Neonatal Status Epilepticus
Kyeong Hun Jung, Yun Hee Kim, Young Se Kwon, Yong Hoon Jun, Soon Ki Kim, Byong Kwan Son
Clin Exp Pediatr. 2005;48(12):1342-1347.   Published online December 15, 2005
Purpose : Among perinatal risk factors, neonatal seizures are one of the strongest independent discriminators of adverse outcome, representing high risks of mortality and neurologic morbidity. This study was undertaken to evaluate the neurologic outcome of neonatal status epilepticus according to underlying etiology, seizure pattern, onset time, and duration. Methods : We reviewed retrospectively 36 neonates(19 males, 17 females) with status...
Case Report
A Case of Atypical Teratoid/Rhabdoid Tumor Arising from the Supratentorial Area
Kyeong Hun Jung, Young Se Kwon, Yong Hun Jun, Soon Ki Kim, Young Jin Hong, Byong Kwan Son, Eun Young Kim, In Suh Park
Clin Exp Pediatr. 2005;48(2):228-231.   Published online February 15, 2005
Atypical teratoid/rhabdoid tumor may arise at any central nervous system location, but it is most commonly located in the cerebellum(60 percent). The incidence of this tumor remains unclear but it occurs most commonly in children less than 2 years of age. This highly malignant tumor shows a rapid progression and nonspecific radiologic findings. We report a case of primary intracranial...
Original Article
Characteristics of Developmentally Delayed Infants and Young Children Who Demonstrated Normal Myelination by Brain MRI
Young Se Kwon, Yong Hoon Jun, Young Jin Hong, Byong Kwan Son, Kyoung Hee Lee
Clin Exp Pediatr. 2004;47(10):1081-1086.   Published online October 15, 2004
Purpose : To evaluate the clinical characteristics of infants and young children who had developmental delay without delayed myelination and dysmyelination. Methods : We retrospectively reviewed 59 cases of developmental disability between July 1996 and June 2001 at Inha University Hospital. Twenty-eight patients showed normal myelination(Group I), while thirty-one patients showed delayed myelination(Group II) by brain MRI. The following clinical records...
Case Report
A Case of Krabbe Disease with Infantile Spasm
Ja Kyoung Kim, Dal Hyun Kim, Bo Young Kang, Young Se Kwon, Young Jin Hong, Byong Kwan Son, Hye Ran Yoon
Clin Exp Pediatr. 2003;46(1):95-99.   Published online January 15, 2003
Krabbe disease is a rare autosomal recessive disorder clinically characterized by retardation in motor development, prominent spasticity, seizures, and optic atrophy. Pathologically, there are many globoid cells in the white matter, in addition to the lack of myelin and the presence of severe gliosis. Hence Krabbe disease is known as globoid cell leukodystrophy. Biochemically, the primary enzymatic deficiency in Krabbe...
A Case of Rhizomelic Chondrodysplasia Punctata Type I
Dal Hyun Kim, Young Se Kwon, Yong Hoon Jun, Young Jin Hong, Byoung Kwan Son, Hye Ran Yoon
Clin Exp Pediatr. 2002;45(12):1585-1590.   Published online December 15, 2002
Rhizomelic chondrodysplasia punctata(RCDP) is a rare autosomal recessive disorder clinically characterized by symmetrical shortening of the proximal limbs, contractures of joints, a typical dysmorphic face, cataracts, and itchyosis. Patients with RCDP can be subdivided into three subgroups based on biochemical analysis and complementation studies. RCDP type I results from mutations in the PEX7 gene encoding the peroxisomal targeting signal type...
A Case of Centronuclear Myopathy
Yun Hee Kim, Yun Hee Kim, Young Se Kwon, Young Se Kwon, Dae Hyun Lim, Dae Hyun Lim, Yong Hun Jun, Yong Hun Jun, Soon Ki Kim, Soon Ki Kim, Young Jin Hong, Young Jin Hong, Byong Kwan Son, Byong Kwan Son, Hae Seung Han, Hea Seung Han
Clin Exp Pediatr. 2002;45(9):1170-1174.   Published online September 15, 2002
Centrinuclear myopathy, an uncommon condition, is one of the congenital myopathies. It is characterized by the presence of central nuclei of muscle cells which can be detected on electronmicroscopy. It is believed to arise as a result of maturational arrest with persistence of microtubes postnatally. We report a boy with generalized hypotonia and muscle weakness who was diagnosed as centrinuclear...
A Case of Partial DiGeorge Syndrome in Prematurity
Tae Jung Sung, Eun Young Ko, Dal Hyon Kim, Ji Eun Oh, Young Se Kwon, Dae Hyun Lim, Byong Kwan Son
Clin Exp Pediatr. 2002;45(3):383-389.   Published online March 15, 2002
We experienced a case of partial DiGeorge syndrome in a 35+5 week premature female infant presented with micrognathia, fish-shaped mouth, beaked nose, nasal regurgitation, obstructive sleep apnea, velopharyngeal insufficiency and late onset hypocalcemic seizures. The chromosome 22q11 microdeletion was found by the FISH method. The lab findings showed serum calcium level of 4.4 mg/dL, ionized calcium level of 0.49 mg/dL,...
A Case of Idiopathic Pulmonary Hemosiderosis Improved with Steroid Inhalation
Young Se Kwon, Jeong Hee Kim, Dae Hyun Lim, Soon Ki Kim, Sei Woo Chung, Byong Kwan Son
Clin Exp Pediatr. 1998;41(8):1153-1156.   Published online August 15, 1998
Original Article
Influences of the Intrapulmonary R→L Shunt on PaO2 and PaCO2 after Instillation of Exogenous Pulmonary Surfactant to Premature Neonates with Respiratory Distress Syndrome
Yoon Hyung Park, Sei Woo Chung, Seung Baik Han, Young Se Kwon, Ji Youn Kim, Woo Sik Cheong, Dae Hyun Lim, Byong Kwan Son
Clin Exp Pediatr. 1997;40(11):1508-1519.   Published online November 15, 1997
Purpose : We are inclined to analyze the relationship between the intrapulmonary right-to-left shunt and the PaO2/PaCO2 after endotracheal single-dose surfactant instillation to premature neonates with respiratory distress syndrome within 6 hours after birth. Methods : From Jan. 1993 to Jun. 1995, we have conducted a clinical trial of surfactant replacement therapy to the premature neonates with respiratory distress syndrome at the neonatal intensive care unit...
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