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Original Article
Neonatology (Perinatology)
Transient intubation for surfactant administration in the treatment of respiratory distress syndrome in extremely premature infants
Ji Won Koh, Jong-Wan Kim, Young Pyo Chang
Clin Exp Pediatr. 2018;61(10):315-321.   Published online September 16, 2018

Purpose: To investigate the effectiveness of transient intubation for surfactant administration and extubated to nasal continuous positive pressure (INSURE) for treatment of respiratory distress syndrome (RDS) and to identify the factors associated with INSURE failure in extremely premature infants. Methods: Eighty-four infants with gestational age less than 28 weeks treated with surfactant administration for RDS for 8 years were included. Perinatal...
Patterns of ischemic injury on brain images in neonatal group B Streptococcal meningitis
Seo Yeol Choi, Jong-Wan Kim, Ji Won Ko, Young Seok Lee, Young Pyo Chang
Clin Exp Pediatr. 2018;61(8):245-252.   Published online August 15, 2018

Purpose: This study investigated patterns of ischemic injury observed in brain images from patients with neonatal group B Streptococcal (GBS) meningitis. Methods: Clinical findings and brain images from eight term or near-term newborn infants with GBS meningitis were reviewed. Results: GBS meningitis was confirmed in all 8 infants via cerebrospinal fluid (CSF) analysis, and patients tested positive for GBS in both blood and CSF cultures....
Fas/FasL expression in the hippocampus of neonatal rat brains follwing hypoxic-ischemic injury
Young Pyo Chang, Myeung Ju Kim, Young Il Lee, Ik Je Im, Jae Ju Cho, Jong-Wan Kim, Sung Moon Yeo
Clin Exp Pediatr. 2006;49(2):198-202.   Published online February 15, 2006
Purpose : Fas is a cell surface receptor that transduces apoptotic death signals. Interaction of extracelluar domain of Fas with Fas ligand(FasL) triggers the apoptotic process in many diseases. We investigated the expression of Fas and FasL in the hippocampus of 7-day-old newborn rat brains following hypoxia-ischemia injury. Methods : The 7-days-old newborn rats were exposed to 8 percent oxygen...
Possible Neuroprotective Role of Exogenous Growth Hormone on Hypoxic-Ischemic Brain Injury in Neonatal Rats
Young Pyo Chang, Mi Kyung Jung, Youn Hee Jee, Jae Ju Cho, Soon Bum Lee, Woo Sung Park, Jong-Wan Kim, Dong Hoon Shin
Clin Exp Pediatr. 2004;47(11):1210-1215.   Published online November 15, 2004
Purpose : This study was performed to evaluate the possible neuroprotective effect of exogenous growth hormone on hypoxic-ischemic brain injury in neonatal rats. Methods : After ligation of the right common carotid artery, seven-day old Sprague-Dawley rats(n= 75) were exposed to 8% oxygen for two hours. In a growth hormone(GH)-treated group(n=25), each animal was subcutanously injected by GH(50 mg/kg, Grotrpin ,...
A Clinical Study of Atypical Kawasaki Disease - A Rate of Coronary Artery Involvement -
Jin-Sook Kim, Young-Yoo Kim, Jong-Wan Kim, Won-Bae Lee, Jin-Han Kang, Kyung-Tai Whang
Clin Exp Pediatr. 2000;43(1):70-77.   Published online January 15, 2000
Purpose : Without a specific diagnostic method, the clinical diagnostic criteria for atypical Kawasaki disease is known as the presence of coronary artery changes in a patient who did not meet the already estabilished clinical criteria. With this criteria, we are put into dilemma because atypical Kawasaki disease should exhibit coronary artery disease. So, we demonstrated the rate of coronary artery involvement in atypical...
Case Report
A Case of Persistent Left Superior Vena Cava Detected on Fetal Echocardiography
Jin Lee, Young-Yoo Kim, Youn-Soo Lee, Jong-Chul Shin, Jong-Wan Kim, Chung-Sik Chun, Kyung-Tai Whang
Clin Exp Pediatr. 1999;42(11):1604-1609.   Published online November 15, 1999
We experienced a case of persistent left superior vena cava draining into the common atrium in a fetus of 26-year-old primigravida. Persistent left superior vena cava is derived from the left cardinal vein. This anomalous vessel usually drains into the right atrium via the coronary sinus and has no physiologic significance. Much less frequently, the left superior vena cava drains...
A Case of Intracoronary Collaterals Misinterpreted as Segmental Stenosis in Kawasaki Disease - Descriptive Method of Coronary Arterial Lesions -
Hee-Sun Chung, Young-Yoo Kim, Seung-Il Kim, Jong-Wan Kim, yung-Tai Whang
Clin Exp Pediatr. 1998;41(12):1709-1716.   Published online December 15, 1998
Visualization of coronary collaterals in coronary arteriography performed in vivo constitutes an important finding, and particularly in the presence of coronary artery disease, it allows observations related to the hemodynamic consequences of the disease process. Undoubtedly, the presence of collateral flow indicates that a compensatory mechanism has developed to ameliorate the detrimental effect of blood flow cessation due to obstruction...
A Case of Tuberculous Pneumonia in Infancy
Joon-Sung Lee, Young-Yoo Kim, Jong-Wan Kim
Clin Exp Pediatr. 1997;40(4):559-566.   Published online April 15, 1997
A rare but serious complication of tuberculosis in a child occurs when the primary infection is progressively destructive. It is difiicult to differentiate from other bacterial pneumonias. We experienced a case of tuberculous pneumonia in a 73-days-old male who presented with cough, fever and progressive dyspnea. Chest X-ray shows diffuse pneumonic consolidation on right upper lung field, Mantoux test was positive...
Original Article
A Clinical Observation of Kawasaki Meningitis and Viral Meningitis
Jae-Ho Hyun, Young-Hoon Kim, Ji-Whan Han, Jong-Wan Kim, Kyung-Tai Whang
Clin Exp Pediatr. 1995;38(6):794-803.   Published online June 15, 1995
Purpose : This study was performed to investigate the clinical characteristics in Kawasaki meningitis and viral meningitis. Methods : A clinical observation and comparison were carried out on 37 patients of Kawasaki disease with meningitis(group A) and 28 patients of Kawasaki disease without meningitis (group B) who were admitted to Catholic Medical Center from July, 1991 to June, 1993 and 100...
Case Report
A Case of Late Infantile Batten's Disease
Kyung-Tae Whang, Jong-Wan Kim, Young-Hoon Kim, Seung-Yun Chung, In-Goo Lee, Je-Geun Chi
Clin Exp Pediatr. 1994;37(12):1745-1751.   Published online December 15, 1994
We experienced a case of late infantile Batten's disease in a 4-year-7-month-old boy who was admitted to child neurology service of Kangnam St. Mary's hospital for evaluation of progressive psychomotor deterioration. He was in quit normal state of development until 3 years of age when his mother first became concerned because he showed such emotional change as crying and fear. Since...
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