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Original Article
Measles Antibodies Measured by Plaque Reduction Neutralization Test in Infants during the First Year of Life
Sung Hee Oh, Hak Won Kim, Younghee Lim, Hahng Lee
Clin Exp Pediatr. 2004;47(8):827-832.   Published online August 15, 2004
Purpose : The 2000-2001 measles epidemic resulted in more than 50,000 cases with the highest attack rate occuring in infants less than one year of age, indicating the necessity of measles immunization before 12 months of age when a measles outbreak occurs again. The study was conducted to measure maternal measles antibody in infants by plaque reduction neutralization test(PRN), for...
Case Report
Two Pediatric Patients with Neutropenia and Thrombocytopenia Associated with Parvovirus B19 Infection
Dong Koo Kim, Young Dai Kim, Ho Jun Lim, Sung Hee Oh, Hahng Lee
Clin Exp Pediatr. 2004;47(3):338-342.   Published online March 15, 2004
Parvovirus B19, a member of the Erythrovirus genus, is the only member of the Parvoviridae family known to be pathogenic in humans. Haematological consequences of B19 infection arise due to a direct cytotoxic effect on erythroid progenitors in bone marrow, resulting in interruption of erythrocyte production. The physiology of host haematopoiesis and competence of the immune response each determines clinical...
Original Article
Experimental Study for the Teratogenic Effect of Gamma-ray on the Heart of Chick Embryo
Yong Whan Jo, Nam Su Kim, Sung Yup Moon, Myeng Gul Yum, Sung Hoon Kim, Ha Chung Chun, Yong Joo Kim, Hahng Lee
Clin Exp Pediatr. 2003;46(6):554-560.   Published online June 15, 2003
Purpose : To investigate the teratogenic effect of gamma-ray on the heart of chick embryo. Methods : 50 rad, 100 rad, 150 rad, 200 rad, 250 rad, and 300 rad of gamma-ray were used to irradiate three days old chick embryos. The control group was not irradiated. After three weeks, the embryos were sacrificed and examined for cardiovascular malformation. Results :...
Analysis of Treatment in Pediatric Germ Cell Tumor
Young Dai Kim, Su Hyun Kim, Ki Joong Kim, Ho Joon Im, Hahng Lee
Clin Exp Pediatr. 2002;45(1):103-108.   Published online January 15, 2002
Purpose : This report is an analysis of our experience with surgery, multi-agent chemotherapy and radiotherapy, in pediatric germ cell tumors(GCTs). Methods : This report included all children(age < 15 years) who were registered between November 1985 and May 2001 with a histologically confirmed diagnosis of GCT and received surgery, chemotherapy and radiotherapy. Retrospective analysis of the medical records of these patients was performed. In...
A Clinical Study on Varicella zoster Virus Infection, Relating Factors and Treatment in Pediatric Cancer Patients
Yoon Sook Chung, Su Hyun Kim, Ki Joong Kim, Hahng Lee
Clin Exp Pediatr. 2001;44(11):1289-1294.   Published online November 15, 2001
Purpose : We performed this study to contribute to the prevention and treatment of Varicella zoster virus infection in pediatric cancer patients through understanding of VZV infection, acyclovir efficacy and varicella vaccination. Methods : A retrospective study was performed by reviewing chart from January 1988 to January 2001. Results : The diseases among 19 cases were leukemia. 12 cases were solid...
Treatment Outcomes in Children with High-Risk Acute Lymphoblastic Leukemia
Kyu Chang Park, Ho Joon Im, Sang Yun Ahn, Hahng Lee
Clin Exp Pediatr. 1999;42(3):383-389.   Published online March 15, 1999
Purpose : The survival rate of those with acute lymphoblastic leukemia(ALL) has been affected by several prognostic factors and previous reports show that a 4-year event-free survival(EFS) for high-risk(HR) group(Age≥10 years and/or WBC≥50,000/mm3 at diagnosis) was approximately 64%. We analyzed treatment outcomes and risk factors in HR-ALL. Methods : Medical records of 27 patients with HR-ALL diagnosed between May, 1985 and...
Erratum
Change in Nutritional Status of Elementary School Children
Sung Kyun Park, Yong Joo Kim, Jeh Hoon Shin, Hahng Lee
Accepted January 1, 1970  
Purpose : The purpose of this study is to compare the present nutritional status with that of previous surveys done in Korea and other advance countries. Methods : We measured the arm circumference and triceps skinfold thickness of 1,009 students of Hanyang Elementary School. We analyzed the arm muscle area and arm fat area. We analyzed the lomgitudinal height and...
Case Report
A Case of Distal Ulcerative Colitis Improved by Budesonide Enemas
Yong Joo Kim, Kwang Seung Shin, Nam Su Kim, Hahng Lee
Clin Exp Pediatr. 1998;41(11):1610-1613.   Published online November 15, 1998
A ten-year-old boy presented with chronic diarrhea and rectal bleeding was studied. Colonoscopic and pathologic diagnosis was distal ulcerative colitis in the sigmoid colon and rectum. Budesonide retention enema(2mg/100ml) was performed every night for 8 weeks. His clinical symptoms, the follow-up colonoscopic and pathologic findings improved in the third week of treatment. His weight did not change and Cushing syndrome...
Original Article
A Clinical Study of Survival Rate and Prognostic Factors in Advanced Neurobalstoma in Children
Seung Yang, Ho Joon Im, Nam Su Kim, Hahng Lee
Clin Exp Pediatr. 1998;41(5):684-694.   Published online May 15, 1998
Purpose : Despite the use of improved therapeutic modalities, long-term survival remains poor in patients in stage Ⅲ or Ⅳ of neurobalstoma and for over 1 year olds at diagnosis. We evaluated the long-term survival rate and related prognostic factors in advanced neuroblastoma. Methods : Twenty-nine children diagnosed with stage Ⅲ or Ⅳ neuroblastoma after 1 year of age, between May...
Recurrent Abdominal Pains:A Field Survey of 1,783 School Children in Seoul
Yong Hwan Cho, Byung Duk Seo, Yong Joo Kim, Nam Su Kim, Hahng Lee
Clin Exp Pediatr. 1997;40(2):199-208.   Published online February 15, 1997
Purpose : We investigated the occurrence rate of recurrent abdominal pain(RAP) in general population of elementary school children, accompanied symptoms, symptomaggravating factors such as emotional stresses, food and personality characters, which time of day the pain develops and whether they visited hospital for RAP. Methods : From 1995. 4. 27. to 1995. 5. 12. questionnaires were given to the parents of 1,783...
Diagnosis and Treatment of Fetal Cardiac Anomalies
Nam Su Kim, Myung Kul Yum, Hahng Lee, Sung Ro Jung, Jung Bae Yoo, Jae Ek Lee
Clin Exp Pediatr. 1996;39(10):1395-1404.   Published online October 15, 1996
Purpose : Fetal echocardiography is used for the prenatal diagnosis of congenital heart disease. Fetal echocardiography allows decisions to be made in advance where the fetal abnormality is not compatible with life after delivery or where early correction is required. Our fetal echocardiographic experience was analysed retrospectively to guide future clinical application. Methods : 138 mothers had fetal echocardiography from April 1992 to December...
Case Report
A Case of Non-IgE-mediated Serosal Eosinophilic Gastroenteritis in a Child with Chronic Asthma
Yong Joo Kim, Ha Baik Lee, Hahng Lee, Eun Kyeong Hong, Hyun Chul Rhim
Clin Exp Pediatr. 1995;38(12):1694-1700.   Published online December 15, 1995
Eosinophilic gastroenteritis(EG) is a chronic disorder in which edsinophils constitute the predominant cell type in the inflammatory infiltrates of the gastrointestinaHGD tract. This disease was first described by Kaiiser in 1937. The clinical symptoms and signs are variable according to the extent of the eosinophilic infiltration(diffuse versus cir¡ⓒ cumscribed) and the depth of the eosinophilic reaction (mucosal, muscular, serosal). Some...
Original Article
A Study on the Necessity to Revise the Present Growth Data for Height and Weight? -Base on Data from the Circumference and Triceps Thickness-
Gi Dong Hwang, Jae Kyung Choi, Jeh Hoon Shin, Nam Soo Kim, In Joon Seol, Hahng Lee
Clin Exp Pediatr. 1995;38(6):745-751.   Published online June 15, 1995
Purpose : Applying the present growth curve(established in 1985) in practice, we noticed some difference. And so, we performed this study to know that is it necessary to revise the present standard data in Korea. Methods : We checked the height and weight of 208 children of one primary school in Seoul. And also, we measured arm circumference and triceps thickness...
A Study on Clinical Characteristics of Maxillary Sinusitis in Korean Children
Dong Nam Kim, Sung Hee Oh, Hahng Lee
Clin Exp Pediatr. 1995;38(3):319-327.   Published online March 15, 1995
Purpose : Paranasal sinusitis, easily overlooked owing to it's benign symptomatology, should be considered when the upper respiratory tract infction persists longer than seven days. Without early recognition and appropriate management, the disease will take a chronic course and the incidence of complications will be increased. The significance of paranasal sinusitis among Korean children has not appropriately been appreciated; therefore,...
Diagnosis of Thoracic Lesions in Children by Fine Needle Aspiration Biopsy
Dong Nam Kim, Nam Su Kim, Hahng Lee, Jong Sung Kim, Suk Chul Jeon
Clin Exp Pediatr. 1994;37(11):1559-1564.   Published online November 15, 1994
To elucidate the clinical availability of FNAB, we reviewed retrospectively medical records of 30 patients who had infiltrative pulmonary lesion or pulmonary nodule of mediastinal mass, and got percutaneous fine needle aspiration biopsy using Wescott needle, 20~22 gauge, at the department of Pediatrics, Hanyang university hospital from July, 1986 to June, 1993. The obtained results were as follow: 1) There were 30...
Occult Mediastinal Ganglioneuroblastoma Presenting with Myoclonic Encephalopathy as Paraneoplastic Syndrome
Hahng Lee, Dong Ki Han, Jae Won Oh, In Joon Seol, Eun Kyung Hong, Seok Chol Jeon
Clin Exp Pediatr. 1994;37(5):695-700.   Published online May 15, 1994
Ganglioneruroblastoma and neuroblastoma are among commonest types of childhood malignancy and a number of unique paraneoplastic syndromes have been associated with both localized and disseminated neuroblastoma. The coincidence of neuroblastoma and myoclonic encephalopathy or other paraneoplastic syndromes occurs relatively rare, and therefore, failure to recognize this association could result in delays in both diagnosis and treatment, and the result...
A Clinical Observation in 14 Children with SLE
Jin Nyoung Park, Jai Kyoung Choi, Ha Baik Lee, Hahng Lee
Clin Exp Pediatr. 1994;37(4):510-519.   Published online April 15, 1994
To elucidate the clinical characteristics of childhood onset systemic lupus erythematosus (SLE), we carried out a retrospective reivew on medical records of fourteen patients who were diagnosed as SLE on the base of 뱓he 1982 revised criteria for the SLE?(by american Rheumatism Association) at the Department of pediatrics, Hanyang University Hospital from January 1980 through August 1992. The results were summerized...
Comparison of Tuberculin Skin Test Results and Adberse Reactions Following BCG Vaccination In Various Infant Groups of Different Ages
In Seung Park, Dong Ki Han, Ho Joon Lim, Sung Hee Oh, Hahng Lee
Clin Exp Pediatr. 1993;36(9):1300-1307.   Published online September 15, 1993
Most authorities including WHO recommended immununizing infants with BCG as early as possible in areas prevalent with tuberculosis, however the optimal time for immunization has not well been characterized. Therefore the investigation was undertaken by vaccinating various infant groups of different ages with BCG and subsequently evaluating for adverse effects and tuberculin reactions, in order to contribute to undestanding the...
Assessment by Question-Naire of Disease Status of the Pupils in Two Primary Schools in Seoul
Jae Kyung Choi, Nam Soo Kim, Soo Jee Moon, Hahng Lee
Clin Exp Pediatr. 1993;36(7):994-1001.   Published online July 15, 1993
We studied the disease status by question-naire in Seoul of the pupils in two primary schools on May, 1991 and carried out statistical analysis of their results. The following results were observed: 1) Total number of answered pupil was 2330;1103 were male and 1227 were female and the ratio of male to female was 1:1.1. Average age was 9.27 years. 2) Number of...
Outcome in Infants of Mothers with Systemic Lupus Erythematosus
Chang Ryul Kim, Young Pyo Chang, Hee Seop Kim, Mi Jung Kim, Byung Il Kim, Jung-Hwan Choi, Chong Ku Yun, Bo Hyun Yoon, Hee Chul Syn, Syng Wook Kim, Seon Yang Park, Hahng Lee
Clin Exp Pediatr. 1993;36(6):791-804.   Published online June 15, 1993
A large proportion of patients with systemic lupus erythematosus(SLE) are women of reproductive age. Their fetal outcome is undoubtedly less favourable than in haelthy women. Although there is no evidence of an increase in congenital anomalies, increased frequencies of miscarriage, stillbirth, growth retardation, and preterm delivery are recognized It mainly depends on the compromise of uteroplacental circulation such as renal...
Case Report
A Case of D13 Ring Chromosome Syndrome
Sung Lae Park, Ho Jun Im, Jae Hun Shin, Hahng Lee, Myung Soo Lyu, Yong Kyun Paik
Clin Exp Pediatr. 1992;35(5):713-717.   Published online May 15, 1992
A case of D13 Ring Chromosome Syndrome, confirmed by chromosome study, was described. She was 8 years and 4 months old, and menifested facial abnormalities, psychomotor retardation and other multiple congenital abnormalities.
A Case of Chronic Granulomatous Disease
So Young Lee, Dae Chul Kim, Sung Hee Oh, Hahng Lee, Hyang Eun Sohn, Wha Soon Chung, Young Hyeh Ko, Moon Hyang Park
Clin Exp Pediatr. 1992;35(5):704-712.   Published online May 15, 1992
Chronic granulomatous disease (CGD) is a hereditary disorder of neutrophil with defective killing and digesting of ingested catalase-positive bacteria or fungi in spite of normal phagocytosis. Dissemination of ingested live organisms results in multiple granuloma in reticuloendothelial system and multiple abscesses manifested by recurrent pus-draining suppurative lymphadenopathy, subcutanous abscess, or impetiginous skin rahses, pheumonitis, and hepatosplenomegaly, ultimately resulting in death. Two...
Original Article
A comparison Study on Soluble FcεR II/CD23 and IL-4 Activities nin the Serum of Children with Allergic and Non-allergic Diseases
Ha-Baik Lee, Han Young Lee, Hahng Lee
Clin Exp Pediatr. 1992;35(3):296-305.   Published online March 15, 1992
Allergy classically rfes to hypersensitivity reaction induced by chemical mediators released from mast cells and basophils activaed by binding allergens contained in house dust, animal dander, pollen, fungus, food and others to IgE (reaginic antibody) bound on these cells. The significance of low affinity Fc receptor for IgE ( FcεR II, CD23, FcεR II/CD23) on B and T lymphocyts, macrohage ,...
Clinical Study of Group B Streptococcal Infection in Infants Less Than Two Months of Age
Hee Jeong Ahn, Ji Yeon Lim, Sung Hee Oh, In Joon Seol, Soo Jee Moon, Hahng Lee
Clin Exp Pediatr. 1992;35(1):17-25.   Published online January 15, 1992
Since 1970, the group B streptococcus has become significant cause of neonatal septicemia and/or meningitis, in recent years the group B streptococcus and E.coli are most common etiologic agent of septicemia and/or meningitis in infants less than two months of age. We have analized 8 cases of group B streptococcal infection who admitted to the department of Pediatrics, Hanyang University...
An epidemiologic study of measles among hospitalized pediatric patients.
Sung Lae Park, Jae Won Oh, Sung Hee Oh, Hahng Lee
Clin Exp Pediatr. 1991;34(10):1356-1364.   Published online October 31, 1991
A clinical study was performed on 197 cases of measles that were admitted to the department pediatrics of Hanyang University Hospital during the period of 5 years from Aug. 1985 to Jul. 1990. The patients with measles were classified as preventable or nonpreventable. We obtained the following results: 1) The incidence of measles was greater during the last study year than the previous years. 2) The age...
A clinical study on varicella zoster virus infection and treatment in children with malignant lymphoproliferative disease.
Hak Won Kim, Jae Won Oh, Sung Hee Oh, Ha Baik Lee, Hahng Lee
Clin Exp Pediatr. 1991;34(9):1246-1254.   Published online September 30, 1991
Vaircella Zoster Virus (VZV) infection is usually a benign disease in normal hosts, but it is known to result in high risk for visceral dissemination and mortality in immunocompromised hosts, as in the children with malignant diseases, especially with malignant lymphoproliferative diseases. Therefore, passive or active immunization and antiviral therapeutic modality have been tried to control visceral dissemination and thus to decrease mortality in...
A study on current immunization status attending an above-middle from class primary school in Seoul.
Jae Won Oh, Sung Lae Park, Sung Hee Oh, Hahng Lee
Clin Exp Pediatr. 1991;34(9):1187-1200.   Published online September 30, 1991
1. Purpose and Methodology The purpose of this survey was to estimate the current immunization status of Korean children by the information gathered by questionnaire distibuted to the parents of all children attending an above-middle class private primary school in Seoul and thereby analizing various factors closely related to the vaccination program as currently administered in Korea. The survey has been conducted by obtaining written answers...
A clinical study on twin.
Ho Joon Im, Sang Yoon Ahn, In Joon Seol, Soo Jee Moon, Hahng Lee
Clin Exp Pediatr. 1991;34(5):621-628.   Published online May 31, 1991
Among the total of 17,991 newborns delivered at Hanyang University Howpital from January 1980 to December 1989, a clinical study was performed on 277 twin pregnancies. The results of the study were as follows: 1) The incidence of twins was 1:64.9. 2) The average male-female sex ratio of twins was 1:1.1, total same sex pairs rate was 79.4% (male-male & female-female) and different sex rate was 20.6%. 3) The...
A case of interstitial pulmonary fibrosis.
Hak Won Kim, Ho Joon Im, In Joon Seol, Ha Baik Lee, Hahng Lee, Seok Chol Jeon, Moon Hyang Park
Clin Exp Pediatr. 1991;34(1):107-114.   Published online January 31, 1991
Interstitial pulmonary fibrosis is a rare, diffuse lug disease which has a tendency to destroy the lung architectures by consequent healing with progressively severe fibrosis. We report with a brief review of literature, one case of a 7-year old female with the typical pictures of interstitial pulmonary fibrosis, histologically on open lung biopsy, and clinically presenting with chronic respiratory difficulty but without definite symptoms...
A Case of Esophageal Variceal Bleeding in a Child Secondary to Portal Hypertension Associated with Cavernous Transformation of the Portal Vein Suggesting Extrahepatic Portal Obstruction.
Sun Yang Hong, Tae Won Oh, Jeong Kook Lee, Hahng Lee, Keun Soo Lee, Seok Chol Jeon, Heung Suk Seo
Clin Exp Pediatr. 1990;33(10):1406-1412.   Published online October 31, 1990
Esophageal variceal bleeding is a rare manifestation in childhood and it usually occurs secondary to portal hypertension. We experienced a case of esophageal variceal bleeding secondary to portal hypertension associated with portal obstruction but with no evidence of liver cirrhosis in a 4-year- and-10-month-old boy who was hospitalized due to hematemesis. He was a product of fullterm normal spontaneous delivery at home unattended by...
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