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Original Article
Cardioprotective Effects of Minocycline in Rat Myocardiac Cell Culture Induced by Hypoxia
Bum Seok Yang, Hye Jin Park, Hong Tae Kim, Jong Won Lee, Dong Suk Lee, Un Seok Nho, Hai Lee Chung, Woo Taek Kim
Clin Exp Pediatr. 2004;47(6):685-690.   Published online June 15, 2004
Purpose : Minocycline appears to reduce the mortality rate of patients with myocardial infarction. Therefore, the cardioprotective effects of minocycline through reduction of apoptosis were studied in a rat myocardiac cell culture induced by hypoxia. Methods : Cultured cells from the hearts of Sprague-Dawley rats were divided into two sets of groups : normoxia groups treated with 5% O2 and...
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