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Original Article
Neuroprotective effects of L-carnitine against oxygen-glucose deprivation in rat primary cortical neurons
Yu Jin Kim, Soo Yoon Kim, Dong Kyung Sung, Yun Sil Chang, Won Soon Park
Clin Exp Pediatr. 2012;55(7):238-248.   Published online July 17, 2012
Purpose

Hypoxic-ischemic encephalopathy is an important cause of neonatal mortality, as this brain injury disrupts normal mitochondrial respiratory activity. Carnitine plays an essential role in mitochondrial fatty acid transport and modulates excess acyl coenzyme A levels. In this study, we investigated whether treatment of primary cultures of rat cortical neurons with L-carnitine was able to prevent neurotoxicity resulting from oxygen-glucose deprivation...

Serum Fatty Acid and Carnitine Levels in Obese Children with Fatty Livers
Jin Bum Lee, Jae Won Lee, Young Mi Hong
Clin Exp Pediatr. 2002;45(9):1083-1089.   Published online September 15, 2002
Purpose : The prevalence of obese children has recently increased. Obesity is known to be associated with complications such as hypertension, fatty liver, hyperlipidemia, and insulin resistance. L-carnitine is an essential cofactor for the transport of long chain fatty acids into mitochondria for β-oxidation. The purpose of this study is to measure serum free fatty acid and carnitine levels, and...
Changes of Serum Fatty Acid and Carnitine Levels after Administration of L-carnitine in Rats
Jae Won Lee, Young Mi Hong
Clin Exp Pediatr. 2002;45(9):1075-1082.   Published online September 15, 2002
Purpose : Obesity is known to be associated with hypertension, dyslipidemia, and fatty liver and is thought to be associated with increased levels of free fatty acids. One of the strategies for decreasing free fatty acid levels is stimulation of hepatic lipid oxidation with L-carnitine. Carnitine is an essential cofactor for transport of long-chain fatty acid into mitochondria for oxidation....
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