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Original Article
Critical Care Medicine
Comparative validity of microalbuminuria versus clinical mortality scores to predict pediatric intensive care unit outcomes
Shifa Nismath, Suchetha S. Rao, B.S. Baliga, Vaman Kulkarni, Gayatri M. Rao
Clin Exp Pediatr. 2020;63(1):20-24.   Published online August 12, 2019
Question: Does microalbuminuria predict mortality in pediatric intensive care unit?
Finding: Positive correlation was found between albumin-creatinine ratio and pediatric intensive care unit stay, organ dysfunction and need of inotropes. Area under the receiver operating characteristic curve for albumin-creatinine ratio was comparable to mortality scores.
Meaning: Microalbuminuria is a good predictor of outcome in pediatric intensive care unit and is comparable with mortality scores.
Comparison of various methods of glomerular filtration rate measurements in children
Na Mi Lee, In Seok Lim
Clin Exp Pediatr. 2009;52(9):999-1004.   Published online September 15, 2009

Purpose:Glomerular filtration rate (GFR) is a fundamental parameter in assessing renal function and predicting the progression of chronic renal disease. Because the use of serum creatinine has several disadvantages, many studies have investigated the use of cystatin C for estimating GFR. We compared creatinine clearance and GFR with formulas using serum creatinine and cystatin C. Methods:We retrospectively analyzed 211 patients...
Effect of renin inhibition on an experimental glomerulonephritis - a preliminary report
Ju Hyung Kang, Jae Kyung Huh, Young Sook Lee, Ji Young Han, Il Soo Ha
Clin Exp Pediatr. 2009;52(8):938-943.   Published online August 15, 2009

Purpose:We performed this study in order to investigate the effect of direct renin inhibition on an experimental animal model with nephrotoxic serum nephritis and tried to give useful information for clinical research and renin inhibitor treatment. Methods:Thirty BALB/c 6-week-old male mice were divided into 4 groups: control group (CO, n=5), control-treatment group with aliskiren (CT, n=5), disease group (DO, n=10), and disease treatment...
The impact of early detection through school urinary screening tests of membranoproliferative glomerulonephritis typeⅠ
Sung-Hoon Chung, Sung-Sin Park, Sung-Do Kim, Byoung-Soo Cho
Clin Exp Pediatr. 2007;50(11):1104-1109.   Published online November 15, 2007
Purpose : Since 1998, school urinary screening tests have been performed on Korean school children. We could detect and treat so many asymptomatic chronic renal disease in early stage. We investigated the efficacy of school urinary screening tests from children with membranoproliferative glomerulonephritis (MPGN) type I. Methods : We analyzed the characteristics and prognosis of 18 patients with MPGN type I...
The Usefulness of Spot Urine Protein/Creatinine Ratio in Evaluating Proteinuria in Children and the Correlation between 24-hour Urinary Protein Amount and Spot Urine Protein/Creatinine Ratio
Seon Young Hong, Ji Young Kim, Woo Yeong Chung
Clin Exp Pediatr. 2003;46(2):173-177.   Published online February 15, 2003
Purpose : Recently, different results about factors affecting accurate quantitation of 24-hr urinary protein(24UP) amount using spot urine protein/creatinine ratio(PCR) have been reported. The current study was designed to evaluate correlation between 24UP amounts and PCR in children, and the effect of 24UP amounts, age, sex, and glomerular filtration rate(GFR) on this correlation. Methods : Among 94 patients who visited the...
Renal Problems in Wilson Disease
Il Soo Ha, Jun Ho Lee, Yeon Ho Choe, Hae Il Cheong, Sei Won Yang, Young Yull Koh, Jeong Kee Seo, Yong Choi
Clin Exp Pediatr. 1999;42(6):817-824.   Published online June 15, 1999
Purpose : Wilson disease is a hereditary metabolic disorder characterized by an accumulation of copper in tissues which sometimes results in renal problems. This study was performed to evaluate the prevalences of the renal problems in Wilson disease and related risk factors. Methods : In 31 patients with Wilson disease, we looked for renal problems by history taking, physical examination...
The Study of Creatinine Clearance in Neonates.
Dong Sun Hong, Moon Ja Kim, Seung Joo Lee, Keun Lee
Clin Exp Pediatr. 1987;30(2):139-143.   Published online February 28, 1987
The creatinine clearance rate, an index of glomerular filtration rate, has been reported to develop according to gestational and postnatal age. The purpose of this study is to examine changes in creatinine clearance with gestational age and postnatal age in preterm and full term healthy neonates. The results were as follows: 1) The creatinine clearance rate increased according to gestational age. 2) The most in creament of creatinine...
Postnatal Changes of Serum Creatinine Levels in Neonates.
Jeong Wan Seo, Seung Joo Lee, Keun Lee
Clin Exp Pediatr. 1986;29(9):948-953.   Published online September 30, 1986
The concentration of creatinine, one of the simple and commonly used indices of glomerular filtration rate in children and adults, has been reported to be appreciably raised and variable during the first month of life. This study examined the effect of gestational age(G.A.) on the postnatal changes of creatinine in preterm and full-term neonates. The results were as follows; 1) The mean...
Estimation of Glomerular Filtration Rate from Plasma Creatinine and Height in Premature and Fullterm Neonates.
Yeong Jee Kim, Keun Lee
Clin Exp Pediatr. 1986;29(7):723-729.   Published online July 31, 1986
In clinical practice, creatinine clearance(Ccr) remains the most commonly used laboratory assessment of glomerular function despite methodological and technical problems of urine collection. Schwartz et al. in 1976,reported that an accurate estimate of glomerular filtration rate (GFR) could be obtained from the simple determinations of plasma creatinine (Per) and body length(L):GFR(ml/min/1.73cm2)=k• L(cm)/Pcr(mg/100ml), (k=constant). The purpose of this investigation is to compare...
A Study on Serum Creatinine and BUN Levels in Newborn Infants.
Shin Chung Jee, Chang Soo Ra
Clin Exp Pediatr. 1985;28(8):741-750.   Published online August 31, 1985
The concept of renal function in the neonate has been that the developing kidney is immature and that glomerular and tubular functions are low for body size as compared with the adult. Authors determined the serum creatinine and blood urea nitrogen (BUN) levels of cord blood in 57 newborn infants(42 normal full-term and 15 premature infants) with gestational age of...
Case Report
Acute Tumor Lysis Syndrome.
Sun Oak Park, In Sil Lee, Hyp Seop Ahn, Yong Choi
Clin Exp Pediatr. 1984;27(3):303-312.   Published online March 31, 1984
To assess the incidence and the effectiveness of preventive measures for tumor lysis syndrome, we analyzed the serial electrolytes levels in leukemia (Group A, 15 patients) and in lymphoma (Group B, 8 patients) patients. The results were 1)Serum LDH were elevated in all of the patients before the chemotherapy. 2)Serum uric acid were also elevated in 8 patients (A 5, B...
Original Article
Serum Levels of Protein, Urea Nitrogen, Uric Acid, Creatinine and Serum Amylase Activity in Normal School Children.
Suck Pill Cho, Byung Wha Park, Hyung Suk Byun, Kyung Reyong Huh, Chull Sohn
Clin Exp Pediatr. 1982;25(2):148-152.   Published online February 28, 1982
Protein, and essential nutrient for the growth of children, is the chief nitrogenous substant in the serum of humans. For the purpose of establishment of the normal data for evaluation of nitrogen balance, we examined the serum levels of urea nitrogen, creatinine, uric acid and serum amylase activity as well as that of protein in 560 normal school children. The...
A Study of Estimation of Maturity of the Newborn Newborn Infant by Neurologic Examination and by Analysis of Creatinine in: Amniotic Fluid and Cord Blood.
Song Soo Moon
Clin Exp Pediatr. 1981;24(4):289-297.   Published online April 15, 1981
Creatinine valuesin the amniotic fluid and cord blood were studied in 28 pregnancies. A scoring system ofr gestational age in the nursery room, based on 6 neurologic and 6 physical maturity, has been applied to that 28 newborn infants sampled. They were admitted to the Obstetric Ward and the Nursery Room of the Cho Sun University Hospital between May 1979...
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