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Original Article

Association of CD4⁺CD25⁺FoxP3⁺ regulatory T cells with natural course of childhood chronic immune thrombocytopenic purpura

Bo Ra Son, Ji Yoon Kim

Clin Exp Pediatr. 2015;58(5):178-182. Published online May 22, 2015

Crossref 7

Purpose

The purpose of this study was to determine the frequency of CD4⁺CD25⁺FoxP3⁺ regulatory T cells (Treg) in the peripheral blood of patients with childhood chronic immune thrombocytopenic purpura (ITP) exhibiting thrombocytopenia and spontaneous remission. The findings of this study indicate the possibility of predicting spontaneous recovery and pathogenesis of childhood chronic ITP.

Methods

Eleven children with chronic ITP (seven thrombocytopenic and four...

DOI: https://doi.org/10.3345/kjp.2015.58.5.178

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