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Evidence-based management guidelines for noncystic fibrosis bronchiectasis in children and adolescents

Clin Exp Pediatr > Accepted Articles
DOI: https://doi.org/10.3345/cep.2023.00871    [Accepted]
Published online January 23, 2024.
Evidence-based management guidelines for noncystic fibrosis bronchiectasis in children and adolescents
Eun Lee1, Kyunghoon Kim2, You Hoon Jeon3, In Suk Sol4, Jong Deok Kim4, Taek Ki Min5, Yoon Ha Hwang6, Hyun-Ju Cho7, Dong In Suh2, Hwan Soo Kim8, Yoon Hee Kim9, Sung-Il Woo10, Yong Ju Lee11, Sungsu Jung12, Hyeon-Jong Yang5, Gwang Cheon Jang13 
1Department of Pediatrics, Chonnam National University Hospital, Chonnam National University Medical School, Gwangju, Korea
2Department of Pediatrics, Seoul National University College of Medicine, Seoul, Korea
3Department of Pediatrics, Hallym University Dongtan Sacred Heart Hospital, Hwaseong, Korea
4Department of Pediatrics, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea
5Pediatric Allergy and Respiratory Center, Department of Pediatrics, Soonchunhyang University Seoul Hospital, Soonchunhyang University College of Medicine, Seoul, Korea
6Department of Pediatrics, Busan St. Mary's Hospital, Busan, Korea
7Department of Pediatrics, International St. Mary's hospital, Catholic Kwandong University, Incheon, Korea
8Department of Pediatrics, College of Medicine, The Catholic University of Korea, Seoul, Korea
9Department of Pediatrics, Yonsei University College of Medicine, Seoul, Korea
10Department of Pediatrics, Chungbuk National University Hospital & College of Medicine, Cheongju, Korea
11Department of Pediatrics, Yongin Severance Hospital, Yonsei University College of Medicine, Yongin, Korea
12Department of Pediatrics, Pusan National University Yangsan Hospital, Yangsan, Korea
13Department of Pediatrics, National Health Insurance Service, Ilsan Hospital, Ilsan, Korea
Correspondence: 
Gwang Cheon Jang, Email: janggwangc@yuhs.ac
Received: 28 June 2023   • Revised: 3 December 2023   • Accepted: 4 December 2023
Abstract
Noncystic fibrosis bronchiectasis is a chronic respiratory disease that carries high socioeconomic and medical burdens and is caused by diverse respiratory illnesses. To improve clinical outcomes, early recognition, active treatment of exacerbations, and prevention of further exacerbations are essential. However, evidence for the treatment and prevention of acute exacerbation of noncystic fibrosis bronchiectasis, especially in children, is lacking. Therefore, the evidence- and consensus-based guidelines for medical and nonmedical treatment strategies for noncystic fibrosis bronchiectasis in children and adolescents were developed by the Korean Academy of Pediatric Allergy and Respiratory Disease using the methods recommended by the Grading of Recommendations Assessment, Development, and Evaluation working group with evidence published through July 2, 2020. This guideline encompasses evidence-based treatment recommendations as well as expert opinions, addressing crucial aspects of the treatment and management of noncystic fibrosis bronchiectasis in children. This includes considerations for antibiotics and airway clearance strategies, particularly in areas where evidence may be limited. Large, well-designed, and controlled studies are required to accumulate further evidence of management strategies for noncystic fibrosis bronchiectasis in children and adolescents.
Key Words: Adolescents, Bronchiectasis, Child, Guidelines, Noncystic fibrosis


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