Journal of the Korean Pediatric Society 1985;28(12):1190-1195.
Published online December 31, 1985.
Lipid Composition of Serum HDL and Fatty Acid Composition of Serum Cholesteryl Esters in Newborn.
Jung Hee Kim1, Dong Wook Kim1, Dae Deok Ahn1, Jung Kwon Lee1, Yoon Ja Kim1, Jung Chull Kim2, Tai Ho Chung2
1Department of Pediatrics, Catholic Hospital, Taegu,Korea
2Department of Biochemistry, Kyungpook National University, School of Medicine, Taegu,Korea
신생아에서 혈청 HDL의 지질조성 및 혈청 Cholesteryl esters 의 지 방산 조성
김정희1, 김동욱1, 안대덕1, 이정권1, 김윤자1, 김정철2, 정태호2
1가톨릭병원 소아과
2경북대학교 의과대학 생화학교실
Abstract
Lipid consumption in early life has been implicated with atherosclerosis in later life. It has been also claimed that lipids contents of serum in early life would reflect coronary atherosclerosis in later life. Present study has undertaken to look for the composition of serum HDL and fatty acid composition of serum cholesteryl esters in newborns. Levels of high density lipoprotein (HDL) cholesterol, HDL-triglycerides, and HDL-phospholipids were determined after elimination of low density and very low density lipoproteins by sodium phophotungstate-Mg precipitation procedure. Fatty acid composition of serum cholesteryl esters was measured by gas-liquid chromatographic method. In comparison with adults, HDL-G, HDL-TG, concentration were decreased, but HDL-PL was significantly increased. However HDL-C/TC, HDL-TG/TG, and HDL-PL/PL ratio were significantly increased compared with those of adults. The statistically significant decrease in 18 : 2/18 : 2 ratio was observed in serum cholesteryl esters of newborns.
Key Words: Newborn, HDL, Fatty acid




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