| A Clinical Study on Patients with Mycoplasma Pneumoniae Pneumonia in Childhood. |
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Yeong Ho Ra, Sung Ho Cha, Sa Joon Chung, Yong Mook Choi, Chang Il Ahn |
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Department of Pediatrics, College of Medicine, Kyung Hee University |
| 소아의 Mycoplasma pneumoniae 폐렴의 임상적 고찰 |
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나영호, 차성호, 정사준, 최용묵, 안창일 |
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경희대학교 의과대학 소아과학교실 |
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| Abstract |
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Clinical features of 96 cases (46 Mycoplasmal pneumonia: Group I, 50 Non-Mycoplasmal pneumo-
nia: Group II) above 2 years of age were studied prospectively from December, 1985 to June, 1986 who
were admitted to the Dept, of Pediatrics, Kyung Hee University Hospital.
The summary of the study is as follows:
1) Among the total 96 cases with pneumonia above 2 years of age, the frequency of Mycoplasma
pneumoniae pneumonia was 48.4% (46 cases) which was based on the results of cold agglutinin test.
Among 21 cases with Mycoplasma pneumoniae pneumonia whom the Indirect Hemagglutinin (IHA)
Tests were performed, positive IHA results were obtained in 15 cases (71.4%).
2) The peak incidences of age were 6—10 years old in the Group I and 2—5 years old in the Group
II, respectively. The mean age of the Group I and Group II were 6.4±2.4 years and 4.4±1.8 years,
respectively and the mean age of Group I was higher than Group II, significantly. (p<0.05). Male to
female ratio of the two groups were 1.5:1 and 1.2:1, respectively.
3) As for the clinical symptoms at presentation, the most frequent symptoms were cough, fever and
sputum, such as usual constitutional symptoms of pneumonia, were noted in order of frequency in
both groups. On the other hands, sore throat and abdominal pain were more frequently noted in the
Group I and the difference was significant (p < 0.05).
4) On physical examination, moist rale was noted most frequently in both groups, but red throat
was more common in the Group I and the difference was significant (p < 0.05).
5) Among the laboratory findings, increased sGPT level was noted more frequently in the Group I
than the Group II and the difference in frequency was significant (p < 0.05). The mean levels of serum
Immunoglobulin G, A and M in the Group I were within normal limits mostly but the increased levels
of IgM were «oted more frequently than the other Immunoglobulins and the differences were significant (p<0.05). 6) As for the findings of chest roentgenography, the most frequent finding was bronchopneumonic
infiltration in the both groups, but hilar adenopathy and pleural effusion were noted in the Group I alone.
Among the sites involved, unilateral involvement was prominent in both group but the
frequency of involvement of lower lobes in the Group I was higher than the Group II significantly (p<0.05),
7) As for the effect of treatment, the duration of coughing was shorter in patients who were treated
with erythromycin within 5 days after onset than the patients who were treated after 5 days, before
10 days after onset. But there was no significant difference in the duration of cough(p>0.1). And the
time of begining of resolution of pneumonic infiltration was faster in the erythromycin-treated
patients than the penicillin-treated patient but there was no significant difference.
8) As for the complications hepatic dysfunction and pleural effusion was observed as 13 cases and
2 cases, respectively in the Group I alone. 9) Mean duration of hospitalization of the Group I and II were 9.5 and 8.5 days respectively, but there was no significant difference (p>0.1).
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| Key Words:
Mycoplasma pneumoniae Pneumonia, Cold agglutinin.
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