| Clinical Evaluation of Bleeding Tendency in Childhood. |
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In Chull Yoo, Gill Hyoun Kim, Sang Man Shin, Sang Jhoo Lee |
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Department of Pediatrics, College of Medicine, Soon Chun Hyang University Seoul, Korea |
| 소아의 출혈 경향에 관한 임상적 고찰 |
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유인철, 김길현, 신상만, 이상주 |
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순천향대학 의학부 소아과학교실 |
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Received: 30 June 1988 • Accepted: 30 June 1988 |
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| Abstract |
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Four hundred and ninety-nine cases of bleeding disorders in childhood who were admitted to
department of pediatrics, Soon Chun Hyang University Hospital during 10 years from July 1977 to
June 1987 were clinically evaluated.
The results obtained were as follows:
1) The incidence of bleeding disorders was 2.97% of total admitted patient. There was no signifi-
cant difference in annual incidence.
2) The peak age of incidence was 4-6 years (23.9%) and the sex ratio of male (61.5%) to female (38.
5%) was 1.6:1.
3) Anaphylactoid purpura (29.9%) was the most common disease which was followed by D.I.C. (25.
9%), leukemia (11.6%), I.T.P. (8.2%), hemorrhagic disease of newborn and infant (7.6%) and aplastic
anemia (4.6%).
4) Anaphylactoid purpura, leukemia, aplastic anemia and non-Hodgkin lymphoma were most
common in 4-6 years and I.T.P. was common in lMo-3 years of age and 4-9 years and D.I.C. was
common under the 3 years of age.
5) The major clinical manifestations were purpura (100%), melena (26%), epistaxis (5%) in vascular
disorder and purpura (56%), epistaxis (43%), easy bruise (32%) in platelet disorders and oozing from
injection site (75%), purpura (46%), hematoma (35%) in plasmatic disorders.
6) The platelet count was below 50,000/cu mm in 72.4% of leukemia, 97.6% of I.T.P. and 91.3% of
aplastic anemia. In hemorrhagic disease of newborn and infant, PT was prolonged in 96.9% of the
cases and all cases of the hemophilia A showed prolonged CT and PTT.
7) The overall mortality rate was 18.0% and peak age in mortality cases were under the IMo old,
the most common cause of death was D.I.C., in which 61 among 129 cases (47.3%) were dead. |
| Key Words:
Bleeding Tendency |
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