Journal of the Korean Pediatric Society 1991;34(3):388-397.
Published online March 31, 1991.
Detection of antigen of RSV and clinical considerations on epinephrine response in wheezy infancy.
Gui Ran Kim1, Seoung Tae Kim1, Hyang Suk Hyun1, Sang Geel Lee1, Im Ju Kang1, Sei Yun Jung2
1Department of Pediatrics, Fatima Hospital, Daegu, Korea
2Department of Clinicopathology, Fatima Hospital, Daegu, Korea
영아기 천명 환아에서의 RSV 항원 검색 및 Epinephrine 반응에 따른 임상적 고찰
김귀란1, 김승태1, 현향숙1, 이상길1, 강임주1, 정세윤2
1대구 파티마병원 소아과
2대구 파티마병원 임상병리과
Received: 24 July 1990   • Accepted: 17 October 1990
Abstract
Clinical studies were made on 126 cases of wheezing infants, who had been admitted to the department of pediatrics, Fatima Hospital, from June 1988 to May 1989. The nasal discharge of patients were examined for detection of antigen of RSV by ELISA method and then we compared RSV antigen positive group with RSV antigen negative group on aspects of epinephrine response and atopic characteristics. The results as follows 1) The antigen of RSV was detected in 19 cases (15.1%) 2) The response to epinephrine was higher in RSV antigen negative group and higher response rate was observed in patients greater than 12 months of age 3) There was no significant difference in family history of atopy, past history of infantile eczema, level of total serum IgE, and skin test to histamine between RSV antigen positive group and negative group. 4) Recurrence of wheezing was higher in RSV antigen negative group, and highest response rate was noted in epinephrine responders of RSV antigen negative group. There was no significant difference in atopic characterics between recurrent and nonrecurrent group, and higher recurrence rate was observed in group, who had been positive skin test to histamine more than 3 mm and family history of atopy.
Key Words: Antigen of RSV, Epinephrine Response, Wheezy Infancy




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