Journal of the Korean Pediatric Society 1991;34(11):1573-1580.
Published online November 30, 1991.
A case of primary hepatocellular carcinoma following vertical transmission of hepatitis B virus in a child.
Soo Kyoung Lee1, Ki Sup Chung1, Sun Won Hong2, Chan Il Park2
1Department of Pediatrics, Yonsei University College of Medicine, Seoul, Korea
2Department of Pathology, Yonsei University College of Medicine, Seoul, Korea
B형 간염 바이러스의 수직감염으로 인하여 소아에서 유발된 원발성 간세포암 1례
이수경1, 정기섭1, 홍순원2, 박찬일2
1연세대학교 의과대학 소아과학교실
2연세대학교 의과대학 병리학교실
Received: 4 June 1991   • Accepted: 26 July 1991
Authors experienced a case of primary hepatocellular carcinoma in a 7 year 9 month old male patient, who was admitted to our hospital due to abdominal pain on right upper quadrant and anorexia during last two months. On family history, his mother was HBs Ag and HBe Ag carrier. On past history, he was admitted to a hospital due to persistant jaundice at 2 months of age, diagnosed as vertical trasmission of hepatitis B virus. At that time, his viral marker study reveraled HBs (+j, Anti HBc (+), HBe Ag(+), Anti HBs (—) and Anti HBe (—). There after, he didn’t have OPD follow up. Physical examination on admission revealed massive hepatosplenomegaly. Diagnostic confirma- tion of primary hepatocellular carcinoma was made by liver scan, abdominal ultrasonography, abdominal CT scan, and needle aspiration biopsy on liver under ultrasono guide.
Key Words: Primary hepatocellular carcinoma, Hepatitis B virus, Vertical transmission

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