| Chlamydia trachomatis respiratory infection in Korean young infants |
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Ki Bae Hong, Youn Shim Shin, Eui-Jung Roh, Eun Hee Chung |
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Department of Pediatrics, College of Medicine, Dankook University, Cheonan, Korea |
| 국내 영유아에서의 Chlamydia trachomatis 호흡기 감염 |
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홍기배, 신연심, 노의정, 정은희 |
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단국대학교 의과대학 소아과학교실 |
Correspondence:
Eun Hee Chung, Email: ehchung@dankook.co.kr
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| Abstract |
Purpose
: Chlamydia trachomatis is one of the most common sexually transmitted diseases and is also a cause of pneumonia in infants. Respiratory infections by respiratory viruses are also common for infants. The objectives of this study were to identify the clinical manifestations and to determine the prevalence of C. trachomatis respiratory infections and coinfections by respiratory viruses in infants younger than 6 months of age.
Methods
: For this study, we enrolled 6 months or younger infants who were admitted to the Dankook University Hospital between January 2002 and July 2007, with respiratory symptoms. Nasopharyngeal aspirates or throat swabs were collected within s d of hospitalization and C. trachomatis was detected using polymerase chain reaction (PCR). Patients who tested positive underwent multiplex PCR for respiratory viruses.
Results
: A total of 690 patients underwent chlamydial PCR testing and 36 (5.2%) had positive results. Of the 36, 28 (78%) were male; 30 were vaginally delivered. From the 36 patients positive for C. trachomatis, 26 underwent multiplex respiratory viral PCR; 12 were coinfected with viruses. Respiratory syncytial virus (RSV) was the most frequent pathogen that was detected in 6 patients. Increased C-reactive protein and fever were significant in patients coinfected with respiratory viruses.
Conclusion
: C. trachomatis can infected in infants delivered by cesarean section as well as in 6 months old or younger infants. Infant with C. trachomatis respiratory infections can also be coinfected with respiratory infection also coinfected with respiratory viruses. Further studies are needed to better understand the prevalence rates of the this infection and its coinfection rate with respiratory viruses. |
| Key Words:
Chlamydia trachomatis, Polymerase chain reaction, Respiratory infection, Coinfection |
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