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A Case of Transverse Myelitis associated with Systemic Lupus Erythematosus

Journal of the Korean Pediatric Society 1998;41(6):831-836.
Published online June 15, 1998.
A Case of Transverse Myelitis associated with Systemic Lupus Erythematosus
Yeong Sim Han, Sun Yeong Park, Min Seop Song, Yeong Sim Han
Department of Pediatrics, College of Medicine, Inje University Pusan Paik Hospital, Pusan, Korea
전신성 홍반성 낭창에 동반된 횡단성 척수염 1례
한영심, 박선영, 송민섭, 황태규
인제의대 부산백병원 소아과학교실
Yeong Sim Han, Email: 1
Transverse myelitis is a rare complication of systemic lupus erythematosus(SLE) and its prognosis is very poor including death or severe neurologic sequelae. We report a 14-year-old girl with transverse myelitis who was not exactly diagnosed as SLE before the onset of neurologic symptoms. Transverse myelitis was diagnosed based on the clinical presentations, cerebrospinal fluid analysis and MRI findings. We employed aggressive treatment with pulse methylprednisolone for acute episodes followed by monthly cyclophosphamide pulse therapy. For the first several months, clinical improvement of the neurologic impairment was noted, but unfortunately her neurological course was on exacerbation.
Key Words: Transverse Myelitis, Systemic Lupus Erythematosus, Pulse Methylprednisolone, Pulse Cyclophosphamide

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