Journal of the Korean Pediatric Society 1996;39(9):1320-1325.
Published online September 15, 1996.
A Case of Pseudomembranous Colitis due to Clostridium difficile
Jung-Hyun Lee, Young-Yoo Kim, Joon-Sung Lee
Department of Pediatrics, Catholic University Medical College, Seoul, Korea
Clostridium difficile에 의한 위막성 대장염 1례
이정현, 김영유, 이준성
가톨릭대학교 의과대학 소아과학교실
Pseudomembranous colitis may result from abnormal growth of toxigenic strains of Clostridium difficile associated with antibiotic-induced alteration of the colonic microbiologic flora. C. difficile, a spore forming gram positive obligate anaerobic bacillus, is part of the normal flora and known to be the major cause of pseudomembranous colitis. We experienced a case of pseudomembranous colitis in a 14-month-old male presented with bloody mucoid diarrhea and fever who had received broad spectrum antibiotics for the treatment of pneumonia. This case was diagnosed with sigmoidoscopy and confirmed by isolation of the organism on culture with selective media TCCFA. All antibiotics were discontinued and vancomycin was administrated orally. He showed a good response.
Key Words: Pseudomembranous Colitis, Clostridium difficile

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